Military University Hospital Prague

Global Prevalence of Keratoconus in the Adult Population: A Systematic Review

To synthesize contemporary estimates of adult keratoconus prevalence worldwide and determine how geography, demographics, and study methodology shape reported rates. We systematically reviewed original studies (2019–2024) quantifying keratoconus in adults. We excluded paediatric-...

Hepatitis A vaccination and its public-health impact in routine prevention and outbreak control: a systematic review and meta-analysis

Background Hepatitis A vaccination is used for routine prevention and outbreak control, but its effectiveness and population-level impact have not been comprehensively synthesised. We aimed to assess vaccine effectiveness, certainty of evidence, and population-level impact. Metho...