Military Medical Academy

Diastolic Pressure- and Heart Rate-Dependent Modulation of Arterial Wave Reflection in a Biophysical Cardiovascular Model

Arterial pressure waveforms are shaped by vascular biomechanics and wave reflection, processes that become increasingly relevant in hypertension and vascular aging. This study aimed to investigate how heart rate (pump frequency) and baseline diastolic pressure modulate pressure w...

Electrospun Nanofibers Loaded with Verbena officinalis Extract as Multifunctional Bioactive Wound Dressings

Background/Objectives: Verbena officinalis has long been used in traditional medicine for treating skin disorders, yet its potential in advanced wound-dressing systems remains insufficiently explored. This study aimed to characterize V. officinalis extracts obtained using differe...

Dinuclear Platinum(II)Complexes Targeting DNA andHuman Serum Albumin: Electrostatic Binding and Apoptosis-Driven AntiproliferativeActivity

Abstract Two novel dinuclear platinum(II) complexes, [{Pt(1,3-pnd)Cl}2(μ-4,4′-bipy)]Cl2 (Pt1) and [{Pt(1,3-pnd)Cl}2(μ-4,4′–SS–bipy)]Cl2 (Pt2), were synthesized and characterized by elemental analysis, UV–vis, and 1H/13C NMR spectroscopy. Spectroscopic and electrochemical studies...