Mie University Hospital

MxA expression in systemic lupus erythematosus –associated myocarditis indicates type I interferon pathway activation

Type I interferon (IFN) pathway activation plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). Myxovirus resistance protein A (MxA) is a surrogate marker of type I IFN activity; however, evidence of local IFN pathway activation in myocarditis associ...

Real-world use of dotinurad and one-year prescription presence by kidney function in older adults

Evidence on dotinurad, a selective urate transporter 1 inhibitor, in older adults with reduced kidney function is limited. We conducted a retrospective cohort study using the Japan Medical Data Center elderly claims database from April 2021 to February 2023 to describe real-world...