Mie University

Remission Trajectories During Low-Intensity Cognitive Behavioural Therapy for Obsessive–Compulsive Disorder: A 2-Year Naturalistic Follow-Up Study

Background and Objectives: Cognitive-behavioural therapy (CBT) for obsessive–compulsive disorder (OCD) has primarily been evaluated in short-term, high-intensity treatment protocols. However, remission trajectories during low-intensity CBT (LiCBT) delivered in routine clinical pr...

Semantic indeterminacy in agentic negotiation: agreement after the recession of the principal

Abstract Agentic AI systems increasingly do not merely respond within negotiations but participate in constituting them: they can add issues, instantiate participant agents, and modify procedural rules while an interaction is under way. Human action can be compositionally produce...

Patient-derived organoids for modeling therapy tolerance, persistence, and resistance in cancer

Therapy resistance remains a major obstacle to durable cancer control. Across cytotoxic chemotherapy, molecularly targeted therapy, immunotherapy, endocrine therapy, and cellular therapy, treatment failure may manifest as primary nonresponse, residual disease, reversible regrowth...

Taxonomic study of the family Pedicellasteridae (Asteroidea: Forcipulatida) from Japanese waters, with descriptions of two new species and one new record

Two new deep-sea species of the family Pedicellasteridae from Japanese waters – Ampheraster phantasma sp. n. and Anteliaster seisuiae sp. n. – are described. These new species represent the first discovery of the genera Ampheraster and Anteliaster from this region. We also report...

Essential Updates in the Surgical Management of Inflammatory Bowel Disease: Current Topics From 2024 to Mid‐2026

ABSTRACT Inflammatory bowel disease management has undergone a major transformation with the introduction of treat‐to‐target strategies and highly effective biologic and small‐molecule therapies. Although these advances have reduced the overall requirement for surgery, operative...

Influence of Footing Geometry on the Behavior of Floating Stone Columns in Soft Clay

Abstract Stone columns are commonly used to improve the bearing capacity and reduce the settlement of soft cohesive soils; however, the effects of footing shape and area replacement ratio on the floating stone column (FSC)–improved ground remain unclear. Short-term field load tes...

Initial surgical results of subcostal uniportal robotic lung resection: a study of the perioperative outcomes and a CUSUM analysis of the learning curve

Abstract Purpose Anatomical lung resection using the da Vinci SP system was recently introduced in Japan. We retrospectively evaluated our initial experience and analyzed the learning curve for the first 53 consecutive cases. Methods Fifty-three patients with primary lung cancer...

MxA expression in systemic lupus erythematosus –associated myocarditis indicates type I interferon pathway activation

Type I interferon (IFN) pathway activation plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). Myxovirus resistance protein A (MxA) is a surrogate marker of type I IFN activity; however, evidence of local IFN pathway activation in myocarditis associ...

Clinical experience and safety of catheter-directed thrombolysis using monteplase for acute iliofemoral deep vein thrombosis: a retrospective single-center analysis

Abstract Iliofemoral deep vein thrombosis (DVT) is associated with an increased risk of post-thrombotic syndrome (PTS), despite anticoagulant therapy. However, since the coronavirus disease 2019 pandemic, no thrombolytic agent has been available under the national health insuranc...

Real-world use of dotinurad and one-year prescription presence by kidney function in older adults

Evidence on dotinurad, a selective urate transporter 1 inhibitor, in older adults with reduced kidney function is limited. We conducted a retrospective cohort study using the Japan Medical Data Center elderly claims database from April 2021 to February 2023 to describe real-world...

Evaluation of fetal left cardiac function by Tei index at different cardiac cycles: An observational study

OBJECTIVE: The Tei index is widely used to evaluate fetal left cardiac function; however, its clinical application is limited by technical difficulties and inconsistent methodology. This study aimed to validate a new method for measuring left cardiac Tei index using Doppler wavef...

Synergistic Effects of Silica and Calcium‐Based Dual Admixtures on the Flowability, Microstructure, and Strength Development in Low‐Carbon Concrete

ABSTRACT Eco‐friendly construction practices have emerged as a cornerstone of modern development. Due to the substantial carbon emissions from cement production, there is a growing demand for supplementary cementitious materials. This study investigated the synergistic effects of...

Quantitative Evaluation of Geographic Atrophy Progression Using Geographic Atrophy Lesion Front Displacement

Purpose: To evaluate the temporal behavior and relative variability of a margin-based metric, lesion front displacement, for quantifying geographic atrophy (GA) progression secondary to age-related macular degeneration and to compare its performance with conventional metrics. Met...