MetroHealth Medical Center

Sikh Youth in Child and Adolescent Psychiatry: A Clinical Perspective

Sikh children and adolescents represent a growing but understudied population in child and adolescent psychiatry. Many Sikh youth navigate complex intersections of religious identity, family expectations, migration experiences, and minority stress, particularly in diaspora contex...

Effect of SGLT2 inhibitors on arrhythmic and device-therapy outcomes in heart failure patients with ICD/CRT-D: a systematic review and meta-analysis

Background Sodium-glucose cotransporter-2 inhibitors (SGLT2i) improve heart failure outcomes, but their association with arrhythmic events and device-therapy endpoints in patients with implantable cardioverter-defibrillator (ICD) or cardiac resynchronization therapy-defibrillator...

National mortality trends due to OSA and respiratory failure in U.S adults from 1999–2023

Obstructive sleep apnea (OSA) and respiratory failure (RF) represent increasing clinical and public health challenges in the United States, yet national trends in mortality remain underexplored. This study evaluates trends in mortality associated with OSA and RF to highlight targ...

Glucagon-like Peptide-1 Receptor Agonists Are Not Associated with Increased Risk of Acute Pancreatitis or Pancreatic Complications, Including Pancreatic Cancer, in Type 2 Diabetes: A Global Propensity-Matched Cohort Study

Introduction: Association between glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and pancreatitis and its long-term complications remains controversial. Using a global electronic health record database, we evaluated pancreatic outcomes following GLP-1 RA initiation in adul...

Ventral Column Spinal Cord Stimulation for Pain Management

Spinal cord stimulation (SCS) is a form of neuromodulation that delivers electrical impulses to the spinal cord, altering pain signals to provide relief from chronic pain. Since its introduction in the 1960s, SCS has primarily targeted the dorsal columns of the spinal cord. While...

Biomarkers in Irritable Bowel Syndrome: Bridging Gut–Brain Mechanisms to Precision Care

Abstract Purpose of Review Irritable bowel syndrome is a common disorder of gut-brain interaction characterized by chronic abdominal pain and altered bowel habits in the absence of structural pathology. Its pathophysiology reflects a complex interplay between the central nervous...

An epidemiological assessment of hemodialysis, continuous kidney replacement therapy, and peritoneal dialysis in pediatric acute kidney injury patients

INTRODUCTION: Hemodialysis (HD), peritoneal dialysis (PD), and continuous kidney replacement therapy (CKRT) are major modalities of kidney replacement therapy (KRT) in pediatric acute kidney injury (AKI). This study uses TriNetX data to identify clinical characteristics of pediat...

Validation of STARZ scoring in very low birth weight (VLBW) neonates in the United States

Abstract Background Acute kidney injury (AKI) is a significant complication in very low birth weight (VLBW) neonates, associated with increased morbidity, mortality, and prolonged hospitalization. Early identification of at-risk infants enables timely interventions. The STARZ sco...