Mental Health Research Canada

Toward clinically actionable lupus biomarkers: a roadmap for research, validation, and translation

Abstract Despite advances in lupus biomarker research, clinical translation has remained limited, leading to delayed diagnosis, imprecise disease monitoring, and trial-and-error treatment approaches. This roadmap, developed by the Lupus Research Alliance’s Biomarker Roadmap Commi...

Differentiating tension-type headache and migraine: integrating cognitive deficits, psychological distress, and pain perception for diagnostic precision

Tension-type headache (TTH) and migraine share overlapping clinical features, which can complicate differential diagnosis. This study examined differences in pain characteristics, psychological distress, and cognitive performance between individuals with TTH and migraine and eval...

Programming of deep brain stimulation of the centromedian nucleus of the thalamus for drug‐resistant epilepsy: A meta‐analysis and proposed programming framework

Abstract Objective Although the centromedian nucleus of the thalamus (CM) is an increasingly considered deep brain stimulation (DBS) target for drug‐resistant epilepsy (DRE), there is significant variability in programming practices, which may contribute to heterogenous outcomes....

A Qualitative Exploration of Mental Health Needs Among Youth Living with Juvenile Spondyloarthritis: Perspectives of Youth and their Caregivers

Objectives To explore the mental health impact and care needs of youth living with Juvenile Spondyloarthritis (JSpA) from the perspective of patients and caregivers. Methods Participants aged 12-18 years with a JSpA diagnosis and their caregivers were recruited in person through...