Memorial University of Newfoundland

Heisenberg Uncertainty Principle on half spaces and orthants: best constants, optimizers and stability

Abstract Though the sharp Heisenberg Uncertainty Principle has been extensively studied in the entire Euclidean spaces, the counterpart on the half spaces or more general orthants has been missing in the literature. We investigate the sharp Heisenberg Uncertainty Principle on ort...

Joint economic and epidemiological modelling of alternative pandemic response strategies

Abstract In an emerging pandemic, policymakers need to make decisions with limited information and require trade-offs between the health impact of the pandemic and the economic costs of the response. Most mathematical models have focused on direct health impacts, neglecting the e...

Development and analysis of a mixed colloid standard with trace elements using AF4-ICP-MS

Environmental context Colloids are small, unstable particles that play important environmental roles in the transport of trace elements and can be analysed using asymmetrical flow field-flow fractionation (AF4) coupled to inductively coupled plasma–mass spectrometry (ICP-MS). A m...

EMMPRIN-mediated metabolism of monocytes promotes disease progression in a mouse model of multiple sclerosis

Monocytes and monocyte-derived macrophages are increasingly recognized as key contributors to the initiation and progression of inflammatory conditions, in part through metabolic reprogramming that drives pathogenic inflammatory phenotypes. However, the upstream mechanisms that c...

The hidden cost of illness: exploring the relationship between seasonal respiratory illness, self-efficacy, and academic achievement of undergraduate science students

<title>Abstract</title> <bold>Background</bold> Seasonal respiratory illnesses (SRIs), including COVID-19, have significantly disrupted university students' academic experiences. This study examines the impact of SRIs on key academic factors such as attendance, self-efficacy, and...

Development and validation of an amyloid PET dementia of the Alzheimer's type (DAT) score

Background Alzheimer's disease (AD) can be debilitating if left untreated, but its progression may be altered through early detection. Objective To develop and evaluate a convolutional neural network (CNN) for detecting AD from amyloid PET brain images and to investigate the regi...

Sustainable Synthesisof Diamide Solvents from SuccinicAnhydride under Microwave Conditions for the Production of Graphenevia Liquid-Phase Exfoliation

Abstract Liquid-phase exfoliation (LPE) is a viable method for the large-scale production of two-dimensional (2D) graphene; however, toxic solvents must be replaced. The microwave synthesis of sustainable succindiamide solvents, namely N,N′-diethyl-N,N′-dibutylsuccindiamide (EBSA...

Synthetic seeds in black huckleberry: clonal fidelity and oxidative balance assessment

Ensuring genetic fidelity and proper antioxidant regulation is essential for synthetic seed technology and conservation of economically important plant species. In this study, we evaluated the effects of plant growth regulators (PGRs) and storage temperature on the germination an...

Assessing Policy Support for Cannabis Health Literacy in Canada: A Document Analysis

Background Canada's legalization of recreational cannabis in 2018 was grounded in a public health approach, with education positioned as a key strategy to promote informed decision-making and reduce harms. However, the extent to which cannabis health literacy (CHL) is supported a...

Acyl-Alkyl-Phosphatidylcholine C40:6 is Potentially a Causal Biomarker for Obesity-Related Knee Osteoarthritis: Data from 4 Independent Cohorts

Objectives To identify potential causal biomarkers for obesity-related knee osteoarthritis (OB+OA+) by metabolome-wide association analysis (MWA) and Mendelian randomization (MR). Methods Four cohorts were included: the Newfoundland Osteoarthritis Study (NFOAS) as discovery, the...