Memorial Hospital of South Bend

Modulation of angiogenic transcription factor ERG via miR-6756 and miR-3190

Angiogenesis plays a crucial role in cancer metastasis as tumors need to establish an increased blood supply to satisfy the demand for oxygen and nutrients. Numerous genes regulate this process, and various mechanisms including microRNAs regulate the expression of these genes. In...

Evaluation of the UK Myeloma Research Alliance risk profile in transplant‐ineligible multiple myeloma patients treated with novel agents

Summary The heterogeneity of multiple myeloma (MM) significantly impacts treatment outcomes. Myeloma risk profile (MRP), introduced by the UK Myeloma Research Alliance, is a novel prognostic model for patients with transplant‐ineligible newly diagnosed MM (TIE‐NDMM) utilizing eas...

Association of low calf circumference and underweight with sarcopenia in older adults with chronic kidney disease: a cross-sectional study

Objectives This community-based, cross-sectional study aimed to evaluate the association of calf circumference and body mass index (BMI) with sarcopenia in older adults with chronic kidney disease (CKD).Methods: Community-dwelling adults aged ≥60 years were enrolled in New Taipei...

Knowledge, practices, and associated factors of intrapartum hepatitis B prevention among obstetric healthcare providers in Kembata Zone public hospitals, Central Ethiopia

Hepatitis B virus (HBV) infection is a major public health concern, particularly in sub-Saharan Africa, including Ethiopia. It is vertically transmitted, highly infectious, and an occupational hazard for healthcare providers, causing acute and chronic liver disease. Despite subop...