Melbourne Sexual Health Centre

Regulatory Policy Changes and Mifepristone Access Through Pharmacies in Australia

Importance In an effort to improve access, the Australian Therapeutic Goods Administration lifted prescribing and dispensing restrictions on mifepristone in August 2023. Mifepristone is approved for medication abortion up to 63 days’ gestation and is marketed in Australia in a co...

Preferred service model and other factors associated with pre-exposure prophylaxis willingness among Indonesian men who have sex with men: analysis of PrEP APPEAL survey

BACKGROUND: Men who have sex with men (MSM) are disproportionately affected by HIV in Indonesia. To prevent transmission, there is a need to scale-up HIV prevention, especially pre-exposure prophylaxis (PrEP). This analysis aims to identify the preferred service model and factors...

Depression and anxiety mediate the association between sleep quality and health-related quality of life in people living with HIV

Sleep disturbances are highly prevalent among people living with HIV (PWH) and frequently co-occur with psychiatric comorbidities such as depression and anxiety. Although these factors independently predict health-related quality of life (HRQoL), the extent to which psychiatric s...

Safety and satisfaction of voluntary medical male circumcision among men who have sex with men in China

PURPOSE: To investigate the safety and satisfaction of circumcision among men who have sex with men (MSM), as voluntary male medical circumcision (VMMC) may be an innovative and acceptable tool for HIV prevention among this population in the future. METHODS: Participants who volu...

Pre-existing systemic and nasal antibodies against avian H5 influenza A viruses vary according to childhood imprinting

Avian influenza A viruses (IAVs) pose a constant pandemic threat, with the recent 2.3.4.4b clade of the H5 subtype causing high pathogenicity and spreading across animal species and geographic locations. Understanding human pre-existing immunity to avian H5 IAV can inform on popu...

Clearance of Treponema pallidum from oral and anal sites after treatment of secondary syphilis: results from a multi-centre, prospective, cross-sectional study

Background Syphilis is increasing worldwide, and secondary syphilis may represent its most infectious stage. Scarce data exist on Treponema pallidum clearance after treatment. We aimed to determine the frequency and load of T. pallidum mucosal shedding, and time to clearance foll...

Unpacking the complexity of contraceptive use among Chinese university students 2014-2024: a systematic review and meta-analysis.

High risks of unintended pregnancies and abortion have been reported among Chinese university students; however, their contraceptive use remains poorly understood. This study synthesised Chinese university students' contraceptive usage to inform the development of context-specifi...

Performance Evaluation in Small Hierarchical Call Centres in a Transient Regime: A Case Study

Abstract This paper addresses a fundamental and practically significant problem in call centre operations, determining optimal call allocation policies and evaluating their performance so as to meet client service targets while minimising staffing costs. Motivated by a problem pr...