Medisch Centrum Haaglanden

Clinical trial barriers in neurostimulation for pediatric drug‐resistant epilepsy

Abstract Objective The NeuroPace responsive neurostimulation (RNS) System effectively treats focal drug‐resistant epilepsy (DRE) in adults but lacks pediatric regulatory approval. Despite effective off‐label pediatric use, systemic device‐trial challenges have impeded label expan...

Assessment of foot perfusion before and after revascularization using quantitative ICG near-infrared fluorescence imaging in patients with and without diabetes mellitus

Diabetes Mellitus(DM) complicates peripheral artery disease (PAD) by increasing neuropathy, ischemia, and amputation risk. Perfusion differences between PAD patients with and without diabetes may support more personalized revascularization strategies than current WIfI-based predi...

The Dutch Prolactinoma Cohort Studies: Cross-sectional Analysis of Females Focusing on the Patient's Perspective

Abstract Purpose To assess the results of patient-reported outcome measures (PROMs) in a national cohort of females with a prolactinoma by disease activity. Methods Females with prolactinoma included in the PRolaCT or ProlaC study were assessed cross-sectionally, comparing patien...