Medical Radiological Research Center

Panel-Specific Optimization and Benchmarking of Copy-Number Callers for ERBB2 Amplification Detection Using the Nanodigmbio NanOnco Plus Panel v3.0

Background/Objectives: ERBB2 amplification is a clinically relevant breast-cancer biomarker, but CNV detection from targeted sequencing depends on assay design, normalization, tumor fraction, and decision rules. We evaluated panel-specific ERBB2 analysis configurations against a...

A differentiated approach to thymectomy in generalized form of myasthenia gravis

Objective. To identify clinical and morphological factors associated with favorable neurological outcomes after extended thymectomy in patients with generalized myasthenia gravis. Material and methods. A single-center retrospective study with prospective component included 103 pa...