Medical Park Gaziantep Hospital

Beyond the Group Mean: Individual Response Heterogeneity in Social Appearance Anxiety, Anxiety and Interpersonal Functioning Following Aesthetic Surgery—A Prospective Controlled Study

Background/Objectives: The psychological consequences of elective aesthetic surgery are usually evaluated by comparing group means, an approach that is insensitive to change that differs in direction across individuals. This prospective controlled study examined both group-level...

Retinal vessel caliber differences between cataract and healthy individuals: a cross-sectional OCT-based analysis

While cataract represents a significant global health burden, evidence directly comparing retinal vessel calibers between cataractous and healthy eyes remains limited. This study characterized retinal vascular morphometry differences between cataractous and healthy eyes, evaluate...

Biochemical Endocrine and Skeletal Findings in Adults with Fabry Disease: A Descriptive Single-Center Study

Background: Endocrine and skeletal findings have previously been reported in Fabry disease (FD), but their interpretation alongside Fabry-specific biochemical markers and multiorgan disease burden remains uncertain. This study descriptively characterized biochemical endocrine fin...

Association Between Nasal Septal Deviation Types and Eustachian Tube Function: A Prospective Observational Study

OBJECTIVE: This study aimed to objectively and subjectively evaluate the effect of nasal septal deviation (NSD) types, classified according to the Baumann system, on Eustachian tube function. METHODS: A total of 107 NSD patients (78 males, 29 females; mean age: 35.39 ± 9.55 years...

External Validation of Clinical Risk Scores and Machine Learning Models for Predicting 30-Day Cardiovascular Risk After Noncardiac Surgery: The PERICARE Study

Background: Machine learning (ML) has emerged as a promising approach for preoperative cardiovascular risk prediction; however, the generalizability of ML models across institutions remains uncertain. Moreover, comprehensive head-to-head comparisons between ML algorithms and esta...

Effects of aerobic, resistance, and combined exercise training on coagulation and fibrinolytic activity in major burns: a preliminary randomized trial

Abstract Background This study aimed to compare the effects of different exercise protocols—resistance, aerobic, and combined resistance-aerobic training—on coagulation and fibrinolytic activity in major burns. Methods This prospective, randomized study included 30 major burn pat...

Modified Mitchell-Banks technique in pediatric inguinal hernia repair: a personalized surgical approach

<title>Abstract</title> The authors have requested that this preprint be removed from Research Square.

Microwave ablation for selective fetal reduction in complicated monochorionic diamniotic twin pregnancies: Experience from a single tertiary center

Abstract Objective To investigate the use of microwave ablation (MWA) for selective fetal reduction in monochorionic twin pregnancies. Methods This retrospective, single‐center case series included consecutive monochorionic diamniotic twin pregnancies that underwent selective fet...

Investigation of the ability of JAM-A molecule to predict clinical outcome, mortality, and symptom onset in patients with acute stroke: a prospective observational single-center cohort study

This study aimed to evaluate the relationship between serum JAM-A levels and both hospital survival and six-month mortality in patients with acute ischemic stroke. It also aimed to investigate the correlation with the time elapsed from symptom onset to event. This prospective, si...

Impact of adjuvant endocrine therapy on disease-free survival in early triple-positive breast cancer: a multicenter retrospective cohort study of the Turkish oncology group

Triple-positive breast cancer (TPBC), characterized by concurrent ER, PR, and HER2 positivity, poses unique therapeutic challenges due to ER–HER2 crosstalk. The optimal adjuvant endocrine therapy in TPBC patients receiving anti-HER2 regimens remains poorly defined. This multicent...

Association of the Systemic Immune-Inflammation Index with CCTA-Derived SYNTAX Scores in Patients with Obstructive Coronary Artery Disease

Background: Systemic inflammation plays an important role in the pathogenesis and progression of coronary artery disease (CAD). The systemic immune-inflammation index (SII) reflects inflammatory and immune status, whereas the platelet-to-lymphocyte ratio (PLR) represents a simple...