Mayo Clinic Health System

Accuracy of commercial pollen forecasts in the United States

Approximately 80 million Americans suffer from seasonal pollen allergies, and many rely on commercial pollen forecasts to guide exposure reduction and medication timing. However, these forecasts are proprietary, and their accuracy has never been comprehensively evaluated. Here, w...

Rheumatoid arthritis, frailty, and outcomes of surgical hospitalizations: A national population‐based analysis

OBJECTIVE: Hospitalization, particularly for surgery, represents a period of heightened stress. We evaluated how frailty attenuates the association of rheumatoid arthritis (RA) with negative health outcomes after elective non-cardiac surgery. METHODS: We conducted a cross-section...

Development and validation of a parsimonious AI-based mortality risk score for heart failure

Abstract Risk stratification in heart failure (HF) supports clinical decisions, yet existing tools face adoption barriers: conventional scores show modest discrimination and depend on specialised tests (i.e., echocardiography), while artificial intelligence (AI) models require ri...

The DRESS/HLH Overlap Syndrome: A Systematic Review of Clinical Features, Triggers, and Outcomes

Background/Objectives: Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome and hemophagocytic lymphohistiocytosis (HLH) are life-threatening conditions characterized by immune dysregulation. Several reports have identified an overlap between these entities; how...

Patient Characteristics and Outcomes of Acute Pancreatitis Managed in a Hospital-at-Home Program: A Multicenter Retrospective Descriptive Study

Background/Objectives: Hospital-at-home (HaH) programs have emerged as an alternative model to brick-and-mortar (BaM) hospital management of acute conditions such as heart failure, pneumonia, pyelonephritis, and chronic obstructive pulmonary disease exacerbation among the others....

Longitudinal Data from a Large, Multi-Target Stool DNA Colorectal Cancer Screening Program

Background & Aims: Multi-target stool DNA (mt-sDNA) is an established stool-based colorectal cancer screening test, yet long-term performance is not well-described. We evaluated follow-up colonoscopy rates & quality, neoplasia yield, and repeat-testing adherence over 10 years wit...

Adolescent-Centered Cannabis Messaging in Clinical Settings: Preliminary Qualitative Insights From Adolescents for Clinicians

BACKGROUND: Youth-directed cannabis messaging is often generic, adult-centered, and does not reflect contemporary patterns of cannabis use. This study examined adolescents' perceptions of cannabis-related messaging and identified messaging strategies they find relevant. METHODS:...