Máxima Medisch Centrum

Evaluation of nationwide variation in post-haemorrhagic ventricular dilatation management following national guideline implementation in the Netherlands

Abstract Purpose Post-haemorrhagic ventricular dilatation (PHVD) is a severe complication of germinal matrix–intraventricular haemorrhage in preterm infants and is associated with significant morbidity and adverse neurodevelopmental outcomes. In 2023, national recommendations for...

Practice variation in hospital care for pelvic organ prolapse and urinary incontinence: an analysis of specialists’ expectations, cross-sectional claims data, and the role of clinical guidelines

Abstract Background Pelvic floor disorders, specifically pelvic organ prolapse and urinary incontinence, are highly prevalent conditions that exhibit substantial practice variation. This study aims to examine the relationship between clinical practice guidelines and practice vari...

Adductor tendinopathy as a source of ongoing chronic postoperative inguinal pain—evaluating outcomes of adductor tenotomy

To evaluate the outcome of an adductor muscle tenotomy in patients with chronic postoperative inguinal pain (CPIP) with a therapy-resistant adductor tendinopathy. In this retrospective cohort study, CPIP patients who underwent an adductor tenotomy between January 2019 and Decembe...

Influence of Ageing on the Pharmacology, Efficacy and Safety of Oral Targeted Therapies for Inflammatory Bowel Disease: Focus on Janus Kinase (JAK) Inhibitors and Sphingosine-1-Phosphate (S1P) Receptor Modulators

Older adults represent a rapidly expanding subgroup of patients with inflammatory bowel disease, yet they remain markedly under-represented in pivotal clinical trials, limiting age-specific estimates of drug benefit and harm. This review synthesises the available evidence on the...

Parent Mental Health From Preterm Birth Through the NICU Stay

OBJECTIVES: Preterm birth and neonatal intensive care unit (NICU) admission are not only extremely stressful for the infant itself but can also impact parental mental health. This Dutch national prospective cohort study aimed to describe the trajectory of parental mental health f...

Multimodal prehabilitation versus no prehabilitation to improve functional capacity, reduce postoperative complications and improve quality of life in colorectal cancer surgery

OBJECTIVES: This is a protocol for a Cochrane review (intervention). The objectives are as follows: To evaluate the benefits and harms of a multimodal prehabilitation programme versus no prehabilitation with respect to functional capacity, postoperative outcomes, and health-relat...

Psychological interventions to improve maternal mental health and resilience during pregnancy in the COVID-19 pandemic: a systematic review

BACKGROUND: During the COVID-19 pandemic, pregnant women experienced increased psychological distress, while access to routine mental health care was often disrupted. Psychological interventions may provide an effective strategy to support maternal mental health under these circu...