Max Planck Institute for Medical Research

Enhancement of hippocampal synaptic AMPA receptor function by the antidepressant tianeptine and by opioid peptides

Management of major depressive disorder (MDD) with conventional therapeutics that enhance monoaminergic neurotransmission requires prolonged treatment prior to clinical benefit and a substantial proportion of patients show little or no improvement. Identifying alternative molecul...

Quantifying Actin Persistence Length in S. pombe and S. cerevisiae : The Impact of Data Size, Filament Length and Fitting Strategy

Actin filaments exhibit isoform and species-specific mechanical properties that are commonly quantified via their persistence length, yet the reliability of such measurements depends not only on the analysis method but also on dataset characteristics. Here, we measure and compare...