Max Planck Institute for Intelligent Systems

Therapeutic-scale CAR-NK microrobots with programmable swarm navigation for targeted solid tumor therapy

An urgent requirement in chimeric antigen receptor (CAR) immune cell therapy [e.g., CAR–natural killer (NK) cells] for solid tumors is to engineer the cells for precise tumor targeting. Meanwhile, medical microrobots can be navigated toward specific target sites using external ma...

Latent causal diffusions for single-cell perturbation modeling

Perturbation screens hold the potential to systematically map regulatory processes at single-cell resolution, yet modeling and predicting transcriptome-wide responses to perturbations remains a major computational challenge. Existing methods often underperform simple baselines, f...

Distribution and voltage dependence of ion channels shape single-neuron computations

Voltage-gated ion channels do not distribute evenly in the plasma membrane of a neuron; they localize to distinct domains where they govern the excitability of the cell and the computations it performs. Informed by electron microscopic reconstructions, models of morphologically r...

Machine-optimized parametric computer assisted design (CAD) of a stable flying wing UAV glider

Abstract Designing a statically stable flying-wing UAV glider is a highly nonlinear problem in which small geometric changes cause large shifts in stability and performance. While prior work has applied gradient-based and gradient-free methods to flying-wing aerodynamic optimizat...

Direct Observation of Propagating Spin Waves in a Spin Hall Nano‐Oscillator

Constriction-based spin Hall nano-oscillators (SHNOs) show great promise for application as highly tunable microwave sources with straightforward scalability toward large coupled networks. However, details of the magnetization dynamics within SHNOs have thus far not been addresse...

Breeding Dispersal of Baltic Dunlins Is Not an Adaptive Response to Unpredictable Nest Flooding

ABSTRACT Human‐driven habitat loss and climate change are rapidly degrading bird breeding habitats worldwide. For ground‐nesting shorebirds using low‐lying shore habitats, nest failure is primarily driven by predation but can also result from intensified temporary flooding. In th...

Time-resolved imaging of antiferromagnetic skyrmion interactions

Abstract Quantifying particle interactions is central to understanding and controlling collective dynamics in particle-based devices such as those comprising skyrmion ensembles. Here we directly visualize, in real time, the nanosecond current-driven dynamics of an antiferromagnet...