Max Planck Institute for Infection Biology

A microbial therapy-mimicry assay shows how spatial resource dynamics control resistance escape

Abstract The evolution of therapy resistance in structured populations such as biofilms and solid tumours is shaped by emergent spatial organization, with profound consequences for evolution-based therapies. However, how treatment reshapes these patterns remains poorly understood...

The limitations of non-mechanistic methods for characterizing pathogen-pathogen interactions: A simulation study

Abstract Pathogen-pathogen interactions occur when infection with one pathogen influences one’s chance of infection or disease due to another. Increasingly, evidence suggests that interactions are a common feature of infectious disease epidemiology. However, due to both the nonli...