Matsuyama Red Cross Hospital

Marked preoperative regression of biopsy-diagnosed microsatellite instability-high colon adenocarcinoma with a small residual traditional serrated adenoma: A case report

Introduction: Marked regression of colorectal cancer before surgery is extremely rare. Microsatellite instability-high (MSI-high) tumors are characterized by a high neoantigen burden and pronounced immunogenicity. Biopsy-associated tissue injury may induce local inflammatory and...