Mater Misericordiae University Hospital

Glycaemic Management and Pregnancy Outcomes in HNF1A ‐ MODY

ABSTRACT Introduction Birthweight of HNF1A ‐affected offspring is largely similar to the background population with rarely reported cases of large for gestational age (LGA) and neonatal hypoglycaemia (NH). Conventional clinical management of pre‐gestational diabetes appears to be...

Autotaxin induces fibrosis in lamina cribrosa cells in glaucoma

Lysophosphatidic acid (LPA) and the enzyme that generates it, autotaxin, have been shown to play a role in fibrosis in the trabecular meshwork in glaucoma, contributing to increased intraocular pressure. We wished to investigate the role of LPA and autotaxin in fibrosis of the la...

Closing the gap in ultrasound probe hygiene: Improving ultrasound probe decontamination through evidence-based interventions

Background and aim: Ultrasound is integral to many aspects of healthcare. Patient harm can occur when ultrasound decontamination is not adequate. Evidence-based guidance exists to inform operators of appropriate practice. A clinical audit was performed to assess compliance with t...

Birdshot chorioretinopathy without classic birdshot lesions: a multimodal imaging case series

To describe atypical presentations of HLA-A29-associated birdshot chorioretinopathy (BCR) in patients without classic cream-coloured birdshot lesions at presentation and to evaluate the contribution of multimodal imaging to the assessment of suspected early disease. Three patient...