Institution
Massachusetts Eye and Ear Infirmary
Recent research
- Health & Medicine
Purpose: To compare real-world pediatric retinal detachment (RD) repair times with the Centers for Medicare and Medicaid Services (CMS) estimates for complex RD surgeries. Methods: A cross-sectional survey was performed of complex pediatric RD perioperative times from pediatric r...
- Health & Medicine
Retinoblastoma is the most common primary intraocular neoplasm in children. Use of radiotherapy has decreased due to the incidence of second malignant neoplasms (SMNs). In our study, photon (n = 42) and proton (n = 66) radiotherapy cohorts had median follow-up of 28.7 and 18.2 ye...
- Health & Medicine
Surgical Management Patterns and Outcomes in Recurrent Corneal Erosion: An IRIS Registry Study
PURPOSE: Surgical management of recurrent corneal erosion (RCE) lacks large-scale evidence, and national patterns of care and procedural outcomes remain incompletely defined. We characterized national practice patterns, repeat surgery rates, and risk factors for surgical failure...
- Health & Medicine
Impact of Neighborhood Socioeconomic Status on Presentation and Treatment of Thyroid Cancer
Abstract Objective We examined associations between multilevel sociodemographic factors and extent of disease at presentation and time to treatment in patients with differentiated thyroid cancer (DTC). Study Design Population‐based study. Setting California Cancer Registry (CCR)....
- BiologyOpen access
The clinical potential of probiotics is increasingly recognized; however, dependence on microbial viability, formulation and storage constraints, and safety considerations in vulnerable populations can limit their broader application. Postbiotics offer an alternative by providing...
- BiologyOpen access
ABSTRACT The immunosuppressive microenvironment limits immunotherapy in triple‐negative breast cancer (TNBC). Interleukin‐15 (IL‐15) activates cytotoxic lymphocytes but is limited by rapid clearance and poor tumor retention. Here, we developed an oncolytic adenovirus encoding IL1...
- Health & MedicineOpen access
Pre-Diagnostic Plasma Endogenous Steroids and the Risk of Exfoliation Glaucoma
Purpose: Exfoliation glaucoma (XFG) is the most common secondary glaucoma. Prior studies suggest a higher incidence in women and links to reproductive history, implying estrogen-related pathways. Metabolomic data also indicated inverse associations with steroid-related plasma met...
- BiologyOpen access
Visual motion is known to influence perceptions of tilt, verticality, and translation, suggesting that optic flow is combined with vestibular cues to estimate orientation relative to gravity. The cerebellar nodulus and ventral uvula (NU) are a prime candidate to perform this comp...
- Health & Medicine
Background: To assess the association between preconception hemithyroidectomy and the risk of gestational hypothyroidism and obstetric outcomes. Methods: This nationwide population-based retrospective cohort study compared euthyroid pregnant women with a history of hemithyroidect...
- Health & MedicineOpen access
Importance of Global Health Opportunities in Residency Selection Among Otolaryngology Applicants
ABSTRACT Introduction Global health has become an increasing priority in medical training. In this cross‐sectional study, we seek to evaluate the importance of a residency program's global health opportunities on otolaryngology‐head and neck surgery (OHNS) applicants' residency s...
- Health & Medicine
The Role of Ankyloglossia as a Protective Factor in Management of Infants With Robin Sequence
OBJECTIVE: Robin sequence (RS) is an anomaly of micrognathia, glossoptosis, and airway obstruction. This study aims to assess the role of ankyloglossia as a protective factor in infants with RS. STUDY DESIGN: Single institution and population-based inpatient registry analysis. SE...