Malabar Cancer Centre

Obesity-driven adipokine signaling in breast cancer: mechanistic insights, therapeutic challenges, and opportunities for precision oncology

Breast cancer is the leading cause of illness and death among women worldwide, with more than 2.3 million new cases diagnosed each year. The incidence and fatality rates are steadily increasing, notably in Asian countries. Obesity has been established as a major and growing risk...

Reproductive factors and prognostic risk stratification in breast cancer: A single-centre study from Kerala with the PC-RISK-5 scoring system

Objectives: To examine the associations between reproductive factors — parity, lactation duration, and menopausal age — and tumour characteristics, molecular subtype, and PC-RISK-5 prognostic scores in women with breast cancer from a tertiary centre in Kerala, India. Material and...

Survival of adolescent and young adult cancer patients in North Malabar: A hospital-based cancer registry data

Objectives: Cancer burden varies by age group. Most cancers affect older adults, including cancers of the colorectum, breast, lung, and prostate. The incidence and patterns of this disease in adolescents and young adults are poorly understood and rarely reported in the literature...