Maine Medical Center

Regional neurodevelopmental and psychosocial encounters for children with CHD: an updated validation cohort from Northern New England

We have previously described how children with complex CHD access developmental and psychosocial services in Maine, most often beyond the reach of the surgical centre. In this follow-up study, we describe a similar pattern for children in Vermont. Of 406 at-risk children between...

A phase 2 pharmacokinetic and pharmacodynamic dose-finding study of oral NEPA for chemotherapy-induced nausea and vomiting in pediatric patients with cancer

Chemotherapy-induced nausea and vomiting (CINV) remains a significant challenge in pediatric oncology, with limited data guiding optimal antiemetic regimens. This phase 2 study evaluated pharmacokinetics (PK), pharmacodynamics, efficacy, and safety of oral netupitant combined wit...