Main Line Health

Liquid Biopsy-Guided Surgical Decision-Making in Oligometastatic Non-Small Cell Lung Cancer: Toward Dynamic Risk Stratification in the Multidisciplinary Era

Oligometastatic non-small cell lung cancer (NSCLC) is defined anatomically by a threshold of five or fewer metastatic lesions across three or fewer organs. That definition is a proxy for a biological question it cannot answer: whether the metastatic process has been arrested at a...

Evaluation of an AI-based digital pathology tool for breast cancer recurrence risk

Hormone receptor-positive (HR+) breast cancer is the most common type among women in the United States. Multigene assays such as Oncotype DX (ODX) assess recurrence risk and chemotherapy benefit but are costly and time-consuming. This exploratory study evaluates the AI-powered Pr...