Maastro Clinic

Multimodal prehabilitation versus no prehabilitation to improve functional capacity, reduce postoperative complications and improve quality of life in colorectal cancer surgery

OBJECTIVES: This is a protocol for a Cochrane review (intervention). The objectives are as follows: To evaluate the benefits and harms of a multimodal prehabilitation programme versus no prehabilitation with respect to functional capacity, postoperative outcomes, and health-relat...

Functional Characterization of Myelodysplastic Syndrome by Multiparameter Flow Cytometry: The Clinical Synergy Between Ki-67 and Bcl-2 and Their Potential Role in Diagnostics and Personalized Therapy

The diagnosis and clinical management of myelodysplastic neoplasms are increasingly challenged by the disease’s inherent heterogeneity, particularly with respect to the diagnosis of low-grade variants. While standardized flow cytometric protocols traditionally rely on static biom...

Technical note: reconstructing dose distributions from manually planned electron boosts in breast radiotherapy

Purpose In breast radiotherapy, delivery of manually-calculated electron boosts limits retrospective dose–response analyses as dose distribution is unavailable. This work evaluates the feasibility of reconstructing dose distributions from manually planned electron boosts in breas...

Multicentre performance and consistency of two deep learning models for malignancy probability estimation of incidental pulmonary nodules

Abstract Objectives A screening-trained deep learning (DL) model (DL1) for pulmonary nodule malignancy probability estimation on CT previously demonstrated good discrimination on a single-centre dataset of incidental nodules. An updated DL model (DL2) was trained on both screenin...