Lyon College

Extended Data for "A theory-informed mixed-methods approach for early implementation assessment in complex intervention trials: a methodological development study".

Methodological materials accompanying the manuscript “A theory-informed mixed-methods approach for early implementation assessment in complex intervention trials: a methodological development study”. The record contains the materials developed for the identification, classificati...

Apparent Intramyocellular Lipid Index Using Spiral Magnetic Resonance Spectroscopic Imaging at 3 T

Abstract Purpose: This work introduces a rapid, high-resolution method based on spiral Magnetic Resonance Spectroscopy Imaging (MRSI) to map the apparent content of intramyocellular (IMCL) and extramyocellular (EMCL) lipids in human skeletal muscle. Methods: Unsuppressed water sp...

Data for: Transposable elements drive phenotypic variation and shape the response to environmental changes in Drosophila melanogaster

Data of the phenotypic measurements and the transposable element insertions with the corresponding scripts.

SLC7A6OS Founder Mutation: A Rare Cause of Progressive Myoclonus Epilepsy Dated to 1100 Years Ago

BACKGROUND: SLC7A6OS c.191A>G is a rare, autosomal recessive cause of progressive myoclonus epilepsy (PME). The c.191A>G variant, first discovered in two families from Türkiye and Portugal, was recently identified in three additional probands from the USA, all of Puerto Rican anc...

Use of cardiac magnetic resonance imaging after hospitalization for acute heart failure: insights from the French nationwide OFICA-2 cohort

Abstract Background Cardiac magnetic resonance (CMR) has a central role in the management of patients with acute heart failure (AHF), but timely access remains heterogeneous. We investigated real-world CMR use in patients hospitalized for AHF and its associations with demographic...

Patients’ and oncologists’ perspectives on shared decision-making and treatment communication in HR+/HER2 − advanced breast cancer: a multicountry survey

Hormone receptor–positive (HR+), human epidermal growth factor receptor 2-negative (HER2−) breast cancer (BC) represents approximately 70% of all cases. In locally advanced or metastatic stages (laBC/mBC), patients’ quality of life (QoL) often worsens, making shared decision-maki...

The top 10 priorities in palliative care research in France: final results of the AXEPRO study

Prioritizing research is essential to reduce waste, particularly in palliative care, a field with historically limited investment. To identify and rank the top 10 unanswered palliative care research questions in France according to patients, caregivers, healthcare professionals a...

Telmisartan for Apolipoprotein E ε4 Carriers as a Candidate Precision Medicine Strategy in Alzheimer’s Disease

The apolipoprotein E ε4 (APOE ε4) allele is the strongest common genetic risk factor for late-onset Alzheimer’s disease and is associated with blood–brain barrier (BBB) dysfunction, cerebrovascular instability, impaired lipid transport, and metabolic dysregulation. These features...