Luye Pharma (China)

Development of discriminatory and biopredictive bicarbonate buffer based dissolution method to screen delayed release formulations

Objective- To develop a novel, discriminatory and biopredictive bicarbonate buffer (BB)-based dissolution method to understand the behaviour of oral delayed release (DR) formulations containing Mesalamine.Significance- Conventional dissolutions have limitations in obtaining discr...

Establishing a single-cell RNA sequencing workflow using EUS-guided fine-needle aspiration for pancreatic ductal adenocarcinoma

Background and Objectives: No unified consensus exists regarding standardized protocols for single-cell RNA sequencing (scRNA-seq) analysis of samples obtained via EUS-guided fine-needle aspiration (EUS-FNA). This study aimed to evaluate the feasibility of applying scRNA-seq to E...

Endophyte-mediated regulatory effects and molecular mechanisms of understory cultivation mode on the metabolism of Panax quinquefolius L.

Elucidating the regulatory mechanisms underlying the effects of understory cultivation on quality characteristics in Panax quinquefolius L. is essential for establishing an ecological cultivation mode. In this study, P. quinquefolius cultivated under understory and field conditio...