Lux Research (United States)

PrOMet: Accurate and Robust Metal‐Binding Site and Type Prediction

ABSTRACT Metal binding to proteins is crucial for many biological functions, yet the prediction of metal‐binding sites and metal types remains underexplored compared to other biomolecular interactions. Despite advances in deep learning, computational methods have achieved limited...

G-screen: scalable protein-aware virtual screening through flexible ligand alignment

Virtual screening has long been a central computational tool for rational ligand discovery, enabling the systematic prioritization of candidate molecules from large chemical libraries. Although docking and related approaches that explicitly account for protein–ligand interactions...

Do South Africa's Corporate Governance Frameworks Undervalue the Company Secretary? Evidence from the Companies Act and King V

The company secretary occupies a constitutively important position within South Africa's corporate governance architecture. Yet both of the country's two principal governance instruments, the Companies Act 71 of 2008 (as amended) and the King V Code on Corporate Governance for So...

3D-printed cranioplasty molds – a technical note on lessons learned and things to avoid

Abstract 3D cranioplasty for cranial defects is growing ever more prevalent. As the technology becomes more accessible, the number of professionals being introduced to it is constantly on the rise. Herein we share our experience with 3D cranioplasty, point out the pitfalls and th...