Luther University

Reduced Carbon Emissions and Chain Elongation during Mixotrophic Fermentation of a Biomass Feedstock

Abstract Anaerobic fermentation of biomass feedstocks using open cultures is a promising technology to produce platform carboxylates. Syngas, a mixture of H2, CO2, and CO, can be sourced sustainably and used to supplement biomass feedstocks as a source of acetyl-CoA, an intermedi...

Future GLP-1 receptor co-agonists and their cardiac effects

Agonists at glucagon-like-peptide-1 receptors (GLP-1R) are becoming approved drugs to treat not only type 2 diabetes and obesity but also cardiac diseases such as coronary heart disease, myocardial infarction and heart failure. Agonism at the GLP-1R can be combined with agonism a...

Contractile effects of Aficamten in the human atrium

Abstract Aficamten is an approved drug to treat hypertrophic cardiomyopathy. Aficamten desensitizes bovine myofilaments against calcium cations. In isolated animal cardiac preparations, aficamten reduced force of contraction (FOC) but its effects on isolated human cardiac prepara...

Ligand Functionalization and Fe Precursor Selection Modulated the Physicochemical Properties of Fe-MOFs and Their Biological Response on Prostate Cancer and Normal Prostate Cells

Abstract Metal-organic frameworks (MOFs) offer modular platforms for cancer nanomedicine, but how metal precursor chemistry and linker functionalization jointly regulate physicochemical properties and biological response remains insufficiently defined. Here, three Fe-based MOFs,...

Comparison of new and recurring post-acute infection syndrome – results from a German population-based cohort

New respiratory infections after or while experiencing post-acute infectious syndromes (PAIS) can lead to resurgence of symptoms. Data comparing symptoms, related impairment, and duration of first and recurring PAIS episodes are lacking. This cross-sectional study was conducted i...

Post-infectious syndromes in the post-pandemic phase among the German general population

BACKGROUND: Persistent symptoms after a respiratory infection can impair daily life, as has been shown, for example, for "long COVID." In this study, we determined the frequency and impact of symptoms that persisted for 12 weeks or more after a respiratory infection. A further en...

Streamlining Habitats Directive Reporting with Open Biodiversity Data: Evidence for the Nature Directives Stress Test [Policy Brief]

Biodiversity monitoring under Article 17 of the EU Habitats Directive (Council Directive 92/43/EEC) remains inconsistent across European Member States. Although all Member States follow the same reporting framework, national assessments are based on national monitoring programmes...