Lurie Children's Hospital

Perspectives on Gender Equity: A National Survey of Pediatric Hospital Medicine Division Leaders

OBJECTIVE: To assess pediatric hospital medicine (PHM) division leaders' perspectives on gender equity in their divisions and organizations. METHODS: In 2025, we conducted a cross-sectional Research Electronic Data Capture survey distributed via email to 236 PHM division leaders....

Predicting Underweight Status in Infants With Cleft Lip and/or Palate in 10 US Children's Hospitals

ObjectiveTo develop and compare models predicting which infants with cleft lip and/or palate (CL/P) will be underweight at 4 months, using multicenter electronic health record data.DesignUsing data from birth to 3 months, we evaluated 63 anthropometric, clinical, healthcare-utili...

Effects of Palliative Oral Etoposide on Survival and Treatment Burden in Patients With Relapsed/Refractory Pediatric Malignancies

Oral etoposide has been given as palliative treatment for pediatric patients with relapsed/refractory malignancies. There is limited literature regarding the efficacy of oral etoposide for relapsed/refractory pediatric malignancies, and even less on its treatment burden for patie...

Reviewing RVUs: Relevant Billing Codes for Infectious Diseases Clinicians

Caitlin Naureckas Li, Joyce Cast, Sameer Patel, Taylor Heald-Sargent, Kathleen Murtagh, Ravi Jhaveri; Reviewing RVUs: Relevant Billing Codes for Infectious

Effectiveness of early initiation of idursulfase in infants and very young children with mucopolysaccharidosis II: a retrospective chart review in siblings

Introduction Enzyme replacement therapy (ERT) with intravenous idursulfase is the standard of care for patients with mucopolysaccharidosis II (MPS II; Hunter syndrome). Data are limited for children aged ≤12 months. This retrospective study evaluated outcomes with early ERT. Meth...

Barriers to Implementing the 2022 Clinical Practice Guidelines for Neonatal Hyperbilirubinemia

OBJECTIVE: To assess whether anticipated weekend follow-up and/or bilirubin rate of rise (ROR) were associated with subthreshold phototherapy (STP) following implementation of the 2022 American Academy of Pediatrics clinical practice guidelines (CPG). PATIENTS AND METHODS: A retr...

Food for thought: a mixed methods analysis of nutrition decision making during bedside rounds in the neonatal intensive care unit

BACKGROUND: Variation in nutrition delivery contributes to poor growth in preterm infants in the neonatal intensive care unit (NICU); however, few studies have examined how clinicians develop nutrition plans. The aim of this research is to describe the nutrition decision-making p...

A compact, wireless fluorimeter system for continuous, real-time monitoring of tissue perfusion via in vivo fluorescence signals

In vivo fluorescence signals provide physiological and pathological insights for the interpretation of biological states associated with anatomical abnormalities or disease. Conventional methods for measuring fluorescence signals rely on bulky, costly instrumentation for imaging...

Comparing Oscillometric and Manual Mean Arterial Pressure Measurements Among Children in the Emergency Department

OBJECTIVE: To evaluate agreement among three approaches to mean arterial pressure (MAP) measurement in children. METHODS: We performed a single-center prospective study of a convenience sample of children (<18 y) presenting to a pediatric emergency department. We compared MAP agr...

National Outcomes of Sepsis in Publicly Insured Children: 2021–2023

OBJECTIVE To identify incidence and factors associated with sepsis mortality. METHODS We conducted a cohort study of all US publicly insured children younger than age 19 years hospitalized with a diagnosis code–based definition of sepsis in 2021–2023 using the Transformed Medicai...

The Transition of Youth With Diabetes From Pediatric to Adult Diabetes Care Services: A Consensus Report of the Joint Working Group of the International Society for Pediatric and Adolescent Diabetes (ISPAD), the European Association for the Study of Diabetes (EASD), and the American Diabetes Association (ADA)

Young adulthood is a period of significant and unique physiological, psychological, sexual, and social upheaval. Related challenges can have an impact on effective diabetes self-management, with high rates of unplanned health care use recorded for many, and consequent increases i...

Burden and Risk Factors for Severe Respiratory Syncytial Virus Infection Among Pediatric Hematopoietic Cell Transplant Recipients

BACKGROUND: Respiratory syncytial virus (RSV) causes substantial morbidity in pediatric hematopoietic cell transplant (HCT) recipients; however, risk factors for severe disease remain incompletely characterized. METHODS: We conducted a multicenter retrospective cohort study acros...

A Comparison of Pediatric Hospitalization Data in Cosmos and the Kids’ Inpatient Database

OBJECTIVE: To compare characteristics of pediatric hospitalizations in Epic Cosmos, an electronic health record-based database that aggregates voluntarily submitted data from across the United States, with nationally representative pediatric inpatient data in the Kids' Inpatient...

Prevalence and Characteristics of Mental Health Interventions Following Pediatric Hospitalization

BACKGROUND AND OBJECTIVES: As survival after pediatric critical illness improves, attention has shifted to post-intensive care syndrome and the long-term mental health of pediatric intensive care unit (PICU) survivors, who have high rates of posttraumatic stress, anxiety, and dep...

Impact of Omitting Observation-Status Data on Hospital Readmission Metric for Pediatric Care

OBJECTIVES: Literature from Medicare beneficiaries suggests that hospital readmission metrics limited to inpatient encounters, omitting observation-status data, may not fully capture hospital performance and affect rankings. The impact of omitting observation-status data on this...

Mental Health Burden and Developmental Timing of Premature Ovarian Insufficiency in Adolescents and Young Adult Females: A Retrospective Cohort Study

POI and EOI are rare but impactful conditions among adolescents and young adults (AYAs). Little is known about the timing and incidence of mental health (MH) conditions among AYAs diagnosed with POI/EOI. Data were collected using MarketScan Medicaid administrative claims among fe...

Validation of AACN’s Healthy Work Environment Assessment Tool–Team

Background In 2024, the American Association of Critical-Care Nurses (AACN) updated the Healthy Work Environment Assessment Tool (HWEAT), renamed HWEAT-Team. Objective Validating HWEAT-Team for interprofessional use. Methods This was a multisite, descriptive, nonexperimental corr...

Beyond Survival: Outpatient Treatment for Functional Recovery After Brain Injury

Abstract Acquired brain injuries (ABIs), including hypoxic-ischemic and traumatic injuries, are leading causes of long-term disability in children. While acute treatment has advanced, many survivors face persistent cognitive, emotional, and physical challenges that require coordi...

Consensus-based eligibility criteria and component definitions for neonatal and infant enhanced recovery pathway: a multidisciplinary delphi study

Abstract Objective The 2020 Enhanced Recovery After Surgery (ERAS®) guidelines for neonatal intestinal surgery have not been widely implemented due to unclear eligibility criteria and poorly defined components. We sought to establish consensus-based eligibility criteria and defin...

Two-Year-Old Girl With Chronic Cough and Lymphadenopathy

A 27-month-old previously healthy girl presented with 3 months of cough and 1 day of fever and rhinorrhea. Her parents had immigrated from Africa, but our patient had been born in the United States and had no notable environmental exposures. An alarming chest radiograph suggested...