Ludwig Boltzmann Institute for Digital Health and Prevention

Applying principal component analysis to identify underlying factors of key performance indicators from microsensor data in basketball games

The present study applied Principal Component Analysis (PCA) to complex microsensor data from 28 elite professional male basketball players across 122 games (1205 player/game samples) during two basketball seasons to reduce data dimensionality and identify underlying factors rela...

Foxn1 regulates epidermal structure, redox balance, and age related changes

Abstract Background Skin aging is a complex process, marked by structural decline, functional impairment, and diminished regenerative capacity. In this study, we shine a spotlight on the transcription factor Foxn1 and its pivotal role in modulating age-related changes in skin arc...

Rehabilitation and the post-intensive care syndrome across the recovery continuum: a narrative review

Purpose Improved survival from critical illness has produced a growing population of intensive care unit (ICU) survivors with new or worsened physical, cognitive, and mental-health impairment, defined as post-intensive care syndrome (PICS), and frequent distress among families/ca...

Keratinocytes with DNA Aberration Induced by UVB Become Susceptible to Ferroptosis

Keratinocytes are key epidermal cells that are highly susceptible to ultraviolet (UV)-induced damage, which can lead to DNA mutations and the development of malignancies. In parallel, UV radiation induces lipid peroxidation (LPO), potentially facilitating the activation of ferrop...