Lucile Packard Children's Hospital

Empiric MRSA Coverage for Children with Osteoarticular Infections: 2015 to 2024

BACKGROUND AND OBJECTIVES Staphylococcus aureus is the most common causative pathogen for children with acute hematogenous osteomyelitis (AHO) and acute bacterial arthritis (ABA). National guidelines recommend empiric coverage for methicillin-resistant S. aureus (MRSA) at hospita...

Navigating Voriconazole in Pediatrics: Dosing Dilemmas and Monitoring Madness

ABSTRACT Safe and effective use of voriconazole in children necessitates therapeutic drug monitoring (TDM) of serum concentrations given the pharmacokinetic variability amongst these patients. Informed by an internal review of voriconazole TDM practices revealing suboptimal perfo...

Disparities in Hospital Length of Stay and Morbidity in Acute Care Pediatric Cardiology Patients

BACKGROUND Multicenter collaborative studies examining disparities in in-hospital outcomes are lacking in pediatric cardiology. We hypothesized that Black and Hispanic patients in pediatric acute care cardiology units (ACCUs) have increased length of stay (LOS) and complications...