Lokman Hekim Üniversitesi

Transformational Leadership and the Reporting of Patient Safety Events Among Emergency Nurses: The Mediating Role of Psychological Safety

Background/Objectives: Underreporting of patient safety events is a persistent problem in high-risk clinical settings such as emergency departments, yet the managerial and psychological conditions associated with reporting remain underexamined. This study aimed to examine the rel...

Association of Platelet–Albumin–Bilirubin and Albumin–Bilirubin Scores with Angiographic No-Reflow in Patients with ST-Segment Elevation Myocardial Infarction Undergoing Primary PCI

Background: The platelet–albumin–bilirubin (PALBI) and albumin–bilirubin (ALBI) scores integrate routinely available laboratory parameters with potential relevance to microvascular injury. We investigated their associations with angiographic no-reflow and incremental predictive v...

Calibration-Aware Patient-Level Prediction of Source-Defined MSIMUT Status in Colorectal Cancer from Whole-Slide Histopathology Images Using Foundation-Model Embeddings

Background/Objectives: Microsatellite instability (MSI) is clinically important in colorectal cancer, but definitive assessment requires molecular or immunohistochemical testing. This study developed a leakage-safe, calibration-aware patient-level framework for predicting a sourc...

Effects of Acupuncture Treatment on Dry Eye Disease in İndividuals Working With Visual Display Terminals

Objective This study aimed to evaluate the effects of a 4-week acupuncture intervention on dry eye symptoms and ocular outcomes in adults with previously diagnosed dry eye disease (DED) and occupational visual display terminal (VDT) exposure. Methods Sixty participants were inclu...

Pan-immune-inflammation Value as a Potential Inflammatory Marker in Autism Spectrum Disorder

Objective: Neuroinflammation and immune dysregulation are implicated in the etiology of autism spectrum disorder (ASD).This study investigated the relationship between inflammatory markers-pan-immune-inflammation value (PIV), systemic immune-inflammation index (SII), neutrophil-t...

Neonatal Niemann–Pick type C: a case series integrating clinical findings, structural modeling and ACMG-based variant interpretation

Abstract Background Niemann–Pick disease type C (NPC) is a rare autosomal recessive lysosomal storage disorder that can present in the neonatal period with cholestasis and hepatosplenomegaly, making early diagnosis challenging. We report a case series of three neonates evaluated...

Examination of hypertension patients’ knowledge levels and self-efficacy regarding their disease

Aim: The present study was conducted with the objective of examining the level of knowledge and self- efficacy of patients with hypertension regarding their disease.Methods: This descriptive study was carried out with 400 patients diagnosed with hypertension who attended the card...

The Effect of Partial Edentulism Patterns on Mandibular Radiomorphometric Indices: A Retrospective Radiological Study

Objective: To compare mandibular cortical structure among fully dentate individuals and patients with Kennedy Class I/II partial edentulism using the Mandibular Cortical Index (MCI), Mental Index (MI) and Panoramic Mandibular Index (PMI), and to test the dentate/edentulous side d...

The Effect of Bioactive Liner Materials on the Bond Strength of Universal Adhesives to Dentin

Objective: This in vitro study aims to investigate how different bioactive base materials influence the bond strength of two universal adhesive systems, Single Bond Universal and Prime&Bond Universal, when applied to dentin-liner complexes. Understanding the interaction between a...

Effects of Different Activation and Obturation Techniques on the Depth of Sealer Penetration into Lateral Canals

Aim:A successful outcome of root canal treatment is contingent upon establishing a three-dimensional seal that encompasses the obturation of lateral and accessory canals. This study investigated the impact of different activation strategies and obturation techniques on the depth...

A Comparative Study of Cardiovascular Risk Calculation Systems and the New PREVENT Model

BACKGROUND: Cardiovascular diseases (CVD) are a largely preventable cause of death worldwide. There are many risk factors that influence CVD, some of which are modifi-able and others non-modifiable. Several systems, such as the widely used Framingham, Reynolds, and the most recen...

Radiographic Evaluation Of The Success Of Root Canal Treatment In Mandibular Premolars: A Retrospective Cross-Sectional Study

Background and Aim: Radiographic assessment is essential forevaluating the technical quality of root canal fillings and periapicalstatus after root canal treatment (RCT). This retrospective crosssectionalstudy assessed the radiographic quality of RCT in mandibularpremolars using...

Pro-regenerative effects of Cydonia oblonga seed mucilage on endothelial and fibroblast cell models

Abstract Objectives Cydonia oblonga seed mucilage is a traditional natural remedy with high water retention capacity and potential bioactivity. However, how it affects wound healing and tissue regeneration is still not fully understood. This study aimed to evaluate the effects of...

Integrative Analysis of Genome Data Using Deep Embedded Clustering to Identify Population Stratification and Functional Gene Modules

AbstractIntroduction: Next-Generation Sequencing (NGS) data analysis faces computational challenges due to high dimensionality. Traditional clustering methods fail to capture biological complexity in human genetic variation. This study introduces Deep Embedded Clustering (DEC) fo...

Association of articular eminence inclination and glenoid fossa roof thickness with sagittal skeletal classes: a CBCT study

<title>Abstract</title> Background This study aimed to evaluate the association between skeletal sagittal malocclusion (based on ANB angle) and temporomandibular joint (TMJ) morphology by assessing bilateral articular eminence inclination (aeı) and glenoid fossa roof thickness, a...

Isolation, genomic characterization, and biocontrol potential of a bacteriophage cocktail against Staphylococcus aureus in milk

The objectives of this study were to isolate, characterize, and evaluate the biocontrol potential of Staphylococcus aureus -targeting bacteriophages in milk. From wastewater and raw milk samples, a total of 19 lytic phages were isolated. Among them SAKAY1298 and SAKAY1306 phages...

How accurate and useful are AI chatbots in interpreting pediatric intraoral photographs?

Accurate recognition of oral conditions is essential for parents to seek timely dental care for their children. However, many parents struggle to identify common pediatric dental problems. Artificial intelligence (AI) tools capable of interpreting clinical images may help bridge...

How does smoking affect the clinical performance of a universal adhesive in non-carious cervical lesions? -An 18-month randomized clinical trial

Smoking has a great impact on oral health status of the patients. As universal adhesives have become a routine dental adhesive choice, understanding the potential impact of smoking on their clinical performance is crucial. This study aimed to determine the 18-month clinical perfo...

The Effect of Root Canal Irrigation Solutions on Surface Roughness and Microhardness of Biodentine

Aim It was aimed to evaluate the effect of a continuous chelation protocol (HEBP/NaOCl) on the microhardness and roughness of Biodentine used for root perforation repair.Material and method Biodentine discs (N=76; 5 mm × 2 mm) were fabricated per manufacturer’s instructions and f...

Post-traumatic dental care, mouthguard use, and preventive behaviour among athletes participating in sports with different contact intensities: a cross-sectional study

Sports-related dental and maxillofacial trauma remains a significant oral health problem in contact sports. This study aimed to investigate dental trauma experience, mouthguard use patterns, and post-traumatic dental care behaviours among elite combat sport athletes and to compar...