Linköping University Hospital

Adaptation of the molecular bacterial load assay for real-time quantification of Mycobacterium tuberculosis in the clinical routine laboratory

ABSTRACT Rapid quantification of Mycobacterium tuberculosis (Mtb) is important for monitoring bacterial load during treatment and in clinical studies. The molecular bacterial load assay detecting Mtb 16S ribosomal RNA (TB-MBLA) can quantify mycobacterial load within hours. As the...

Correlations between monitor alarm workload and overall workload in Swedish emergency departments: a prospective multicenter cross-sectional study

<title>Abstract</title> Background Emergency departments (ED) operate under conditions of high clinical demands, time-critical decisions and tasks. These characteristics can result in substantial workload on staff, which increases the risk of diagnostic errors and procedural dela...

Trajectories of refraction and strabismus from 2.5 to 12 years in a national cohort of extremely preterm children‐ the Extremely Preterm Infants in Sweden Study (EXPRESS)

Abstract Purpose To investigate the longitudinal development of refraction and strabismus in a national cohort of children born extremely preterm (EPT) and find relations to perinatal events and neurodevelopmental outcomes. Methods All surviving children born &lt;27‐gestation wee...

Physician-Modified Cook Zenith Alpha Thoracic Endovascular Graft with Preservation of Active Fixation Barbs: A Step-by-Step Technical Guide

Physician-modified endografts (PMEGs) represent an important treatment option for urgent and semi-urgent complex abdominal aortic aneurysms (cAAAs). The Zenith Alpha Thoracic Endovascular Graft (Cook Medical, Bloomington, IN, USA) is a common choice for PMEGs due to its low strut...

Associations between organizational readiness and implementation fidelity in national implementation of WHO’s labour care guide in Sweden: a prospective observational study

Abstract Background During 2024 and 2025, an adapted version of the World Health Organization’s Labour Care Guide was implemented in approximately half of Sweden’s labor wards within the PICRINO trial. Organizational readiness is widely regarded as a key determinant of successful...

Impact of intraoperative CT on implant accuracy and reoperation rates in orbital floor reconstruction

BACKGROUND: Implant malposition is a leading cause of reoperation after orbital floor reconstruction. Intraoperative computed tomography (CT) enables immediate assessment and correction, however its impact on implant positioning accuracy and outcomes remains insufficiently studie...