Liaquat University of Medical & Health Sciences

Dexamethasone versus triamcinolone acetonide for the management of postoperative inflammation following cataract surgery

Background: Cataract remains the leading cause of reversible blindness worldwide, particularly in low-resource settings. Effective control of postoperative inflammation is essential to prevent complications such as cystoid macular edema and raised intraocular pressure. Dexamethas...

Efficacy and Safety of Cisplatin Versus Carboplatin for Patients With Squamous Cell Carcinoma of Head and Neck: A Systematic Review and Meta‐Analysis

ABSTRACT Background Cisplatin‐ and carboplatin‐based regimens are widely used in the treatment of head and neck squamous cell carcinoma (HNSCC), yet comparative evidence on survival and toxicity outcomes remains limited. While cisplatin is standard in many settings, carboplatin i...

High-flow nasal cannula versus conventional oxygen therapy in adults with acute hypoxemic respiratory failure: an updated systematic review, meta-analysis and trial sequential analysis

HFNC oxygen therapy is widely used for acute hypoxemic respiratory failure (AHRF), yet its superiority over conventional oxygen therapy (COT) remains uncertain. This meta-analysis evaluated HFNC efficacy and safety in adults with AHRF. Five databases were searched from January 20...

First Report of Banana End Rot Caused by Corynespora torulosa in Pakistan

Banana (Musa acuminata Colla) is an important crop in Sindh, Pakistan, where Basrai (Dwarf Cavendish) is the dominant cultivar (Muhammad et al. 2020). In November 2023, banana end rot (BER) was observed on Basrai fruits in Naushehro Feroze District (26.7878°N, 68.2680°E). Only 3...

Comparative Effectiveness and Safety of Low Molecular Weight Heparin, Rivaroxaban, Apixaban, and Warfarin in Postoperative Thromboprophylaxis and Deep Vein Thrombosis Management: A Systematic Review and Meta-Analysis

ABSTRACT: Prophylactic venous thrombosis or more commonly known as postoperative "blood clots" is a problem in all surgeries and is known as venous thromboembolism or VTE, and continues to be a significant cause of postoperative morbidity and mortality. For the prevention and tre...

Low-dose combination antihypertensive therapy versus standard therapy in adults with hypertension: a systematic review and meta-analysis of randomized controlled trials

Abstract Background Low-dose combination-based antihypertensive therapy has emerged as a promising strategy to improve blood pressure (BP) control while minimizing dose-related adverse effects. However, evidence comparing its efficacy and safety with conventional antihypertensive...

National trends in heart failure and hyperlipidemia related mortality in the United States, 1999–2024

Cardiovascular disease remains the leading cause of death in the United States, with heart failure (HF) and hyperlipidemia substantially contributing to mortality. This study aimed to examine national trends in HF-related mortality with coexisting hyperlipidemia from 1999 to 2024...

Post-Procedural Angiography-Based Physiological Indices and Clinical Outcomes After Drug-Coated Balloon Treatment of In-Stent Restenosis

Drug-coated balloons (DCBs) represent an accepted approach for in-stent restenosis (ISR); however, post-procedural predictors for risk stratification remain limited. Angiography-based physiological parameters, including quantitative flow ratio (QFR), microvascular QFR (μQFR), and...

Association between minimum dietary diversity and growth among children aged 6–23 months in Pakistan: a propensity score matching approach

Minimum dietary diversity (MDD) is an important indicator of complementary feeding quality and has been associated with child nutritional status. This study examines the association between adequate MDD and growth outcomes among children aged 6–23 months in Pakistan using a poole...

Angiography-Derived vs Wire-Based Physiological Assessment in Coronary Artery Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

This study aimed to determine whether angiography-based physiological assessment yields clinical outcomes comparable to those of conventional wire-based pressure measurements in patients with coronary artery disease (CAD) undergoing evaluation of intermediate coronary stenoses. A...

Comments on Does Local Excision Without Salvage Surgery Affect the Prognostic Outcome of Patients With Malignant Colorectal Polyp? A Long‐Term Survival Analysis

Data sharing not applicable to this article as no datasets were generated or analysed during the current study.

HPV DNA negativity following AHCC or nonavalent vaccination or their combination in women with persistent HPV infection without HSIL

Persistent infection with high-risk human papillomavirus (HR-HPV) is a common clinical condition for which no validated systemic antiviral therapy is currently available, and in the absence of high-grade cervical lesions management is generally limited to surveillance. Active Hex...

Temporal trends and demographic disparities in constipation-associated mortality in the United States, 1999–2024

Constipation is common and managed as benign; however, refractory disease can progress through fecal impaction to stercoral colitis, perforation, and sepsis. The national mortality trends are unmapped. Serial cross-sectional CDC WONDER multiple-cause analysis, US adults ≥ 25 year...

Examining the role of actual behavioral control in adolescent upcycling behavior

This study was conducted to explore upcycling behaviour using the knowledge, attitude, and practice (KAP) model, incorporating actual behavioural control (ABC) as a moderating variable. While previous studies on upcycling have primarily focused on the industrial sector’s perspect...