Liaquat National Hospital

Efficacy and Safety of Cisplatin Versus Carboplatin for Patients With Squamous Cell Carcinoma of Head and Neck: A Systematic Review and Meta‐Analysis

ABSTRACT Background Cisplatin‐ and carboplatin‐based regimens are widely used in the treatment of head and neck squamous cell carcinoma (HNSCC), yet comparative evidence on survival and toxicity outcomes remains limited. While cisplatin is standard in many settings, carboplatin i...

Molecular detection and risk factors of carbapenemase -encoding gene among the Gram-negative uropathogens associated with catheter-associated urinary tract infection

Carbapenem-resistant Gram-negative bacteria frequently cause catheter-associated urinary tract infections (CA-UTIs). The objectives of this study included investigating prevalence, drug-resistance mechanisms, and risk factors associated with the infections caused by carbapenemase...

Hepatitis E vaccination in women of childbearing age: safety and tolerability outcomes

Abstract Background and objective Hepatitis E virus is a major cause of acute viral hepatitis and is endemic in Pakistan, where it contributes substantially to morbidity and mortality among women of childbearing age. The Hecolin vaccine is a potentially useful preventive measure,...

Management of metastatic spinal disease in low- and middle-income countries: an international survey of practices and challenges in Latin America

Spinal metastases impose urgent diagnostic and therapeutic demands; however, evidence from low- and middle-income countries (LMICs) in Latin America is sparse. We aimed to characterize real-world practices, access gaps, and priorities to in-form context-adapted guidelines. We con...

Exploring Institutional factors of resilience in undergraduate medical training: a thematic inquiry into experiences of medical students

Resilience is an essential attribute for medical students to manage academic demands and sustain well-being during training. While resilience has traditionally been studied at the individual level, less attention has been given to institutional factors that shape its development....

Breast Cancer Knowledge and Screening Barriers Among Female University Students of Pakistan

Breast cancer is a leading public health concern among low- and middle-income countries, primarily due to inadequate knowledge and lack of early detection practices. This study aimed to assess knowledge about the signs and symptoms, risk factors, and screening procedures for brea...

Previously undiagnosed pulmonary arteriovenous malformation in hereditary hemorrhagic telangiectasia presenting as a brain abscess: a case report

Abstract Introduction Pulmonary arteriovenous malformations (PAVMs) are abnormal vascular connections that predispose to paradoxical embolism and brain abscess formation. They often remain undetected until severe complications occur, posing significant diagnostic challenges. Case...