Liaoning University of Traditional Chinese Medicine

Interpretable machine learning for identifying mild cognitive impairment among Chinese patients with obstructive sleep apnea: a multicenter cross-sectional study

Mild cognitive impairment (MCI) is clinically relevant in obstructive sleep apnea (OSA). We developed and externally validated an interpretable machine-learning model for concurrent clinically defined MCI to support prioritization for formal cognitive assessment rather than diagn...

The effect of compression stockings on patients with lower extremity venous ulcers: A meta-analysis

Objective This study aims to systematically evaluate the efficacy and safety of compression stockings compared with other active compression modalities and surgical interventions in the management of venous leg ulcers, and to explore the impacts of intervention duration, reported...

Dignity of older adults among nursing homes: A scoping review

BackgroundDignity is a core concept in geriatric care. However, current attention to dignity-related care issues faced by older adults in nursing homes remains insufficient. There is a notable lack of systematic and proactive support measures in both theoretical research and prac...

Latent profiles and associated factors of self-management behaviours among middle-aged and older adults with type 2 diabetes

Type 2 diabetes requires sustained self-management across multiple behavioural domains, yet middle-aged and older adults may not follow a single high-versus-low pattern. This study aimed to identify latent profiles of self-management behaviours among middle-aged and older adults...

Multi-omics analysis of skin tissue metabolome and proteome reveals the repigment effect of Qubai tincture against vitiligo in mice

BackgroundVitiligo is an autoimmune-mediated dermatological disorder characterized by the progressive loss of functional melanocytes, leading to patchy skin depigmentation. The traditional Chinese medicine (TCM) strategy for treating vitiligo centers on nourishing the liver and k...

Efficacy and evidence certainty of traditional Chinese exercises for musculoskeletal disorders: an umbrella review of meta-analyses

Objectives To comprehensively evaluate the efficacy and exercise prescription parameters of traditional Chinese exercises (TCEs) on health outcomes in patients with musculoskeletal disorders (MSDs) and rigorously assess the certainty of the evidence. Design Umbrella review. Data...

AB4-Loaded Nanomicelle Hydrogel Promotes Targeting of the Dysregulated Diabetic Wound Microenvironment via Coordinated Multistage Repair

(1) Background: Impaired diabetic wound healing stems from systemic dysregulation of the wound-healing cascade under hyperglycemic conditions, producing a disordered microenvironment marked by sustained inflammation, defective angiogenesis, and aberrant extracellular matrix remod...