Levine Cancer Institute

Early Satiety in Cancer ‒ the Symptom Experience: Exploratory Cross-Sectional Cohort Study

Background Early satiety (ES) is a common symptom in several conditions, including cancer. Despite presenting at all cancer stages, little is known about how patients describe ES. This study aimed to explore the lived experience of those with ES. Methods A cross-sectional study w...

Pharmacokinetic and pharmacodynamic sub-study of trans-arterial vs. intravenous gemcitabine in the TIGeR-PaC phase 3 clinical trial

Abstract Purpose Localized intra-arterial delivery of gemcitabine (IAG) may provide advantages in terms of increased tissue concentration and decreased systemic dosing. We hypothesized IAG may result in decreased systemic gemcitabine concentration and associated side effects due...