Leibniz Institute of Polymer Research

Polystyrene-Grafted Chain-Walking Polyethylene: Precision Synthesis and Multidimensional Analysis of Composition, Conformation, and Topology

Abstract Polystyrene-grafted chain-walking polyethylene graft copolymers were synthesized by grafting living polystyryl anions onto ester-functionalized chain-walking polyethylene backbones. Two complementary sample series were designed to address questions of synthetic precision...

Printing‐Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling

ABSTRACT The limitations of electrical neuromodulation are driving the development of neuroprosthetic systems enhanced with complementary modalities. A key technological challenge however remains the integration of the necessary hardware components (optical, thermal, fluidic, ele...

PEG-Heparin hydrogels allow for the assessment of breast cancer tumouroid response to anti-cancer treatment for personalised medicine

Objectives The validation of accurate three-dimensional (3D) models holds significant importance for anti-cancer drug development and screening processes, aiming to minimise the time and resources lost during their development using conventional procedures. Here, we investigated...

Reprocessable Elastomeric Networks Produced via Trimesic Acid‐Induced β‐Hydroxy Ester Crosslinking of Epoxidized Natural Rubber With Tunable Mechanical Properties

ABSTRACT Trimesic acid (TMA) has been employed as a trifunctional crosslinker to develop dynamic epoxidized natural rubber (ENR) networks through zinc‐acetate‐catalyzed formation of β‐hydroxy ester linkages. Unlike conventional sulfur‐vulcanized networks, which are commonly descr...

Photo‐Degradable Polyester Networks and Multi‐Photon Printed Objects Based on Cyclic Ketene Acetals

ABSTRACT Radical ring‐opening polymerization (RROP) of cyclic ketene acetals (CKAs) constitutes a powerful avenue to biodegradable polyesters via radical polymerization. CKA‐based degradable polymers have been established mainly as linear polymers, while networks from CKA‐based R...

A pancreatic cancer organoid-macrophage co-culture using starPEG-heparin hydrogel deciphers tumor-immune cell interactions

Abstract Macrophages are among the most abundant immune cells in the pancreatic ductal adenocarcinoma (PDAC) tumor microenvironment (TME) and play a key role in regulating the immunosuppressive niche that facilitates tumor growth. Although recent three-dimensional (3D) culture sy...

Born to Condense: Polysomes Drive Co-Translational Condensation of Biomolecular Condensate Proteins

This repository contains all necessary raw data and processed data used to generate the figures in this study.