Leibniz-Institute for Food Systems Biology at the Technical University of Munich

Mechanistic Insights Into Noble Metal Nanoparticle Antimicrobial Activity through Correlative SEM–SEI‐XPS Analysis

This article presents a correlative analytical strategy for studying nanoparticle-microbe interactions. Understanding the intracellular transformations of metallic nanoparticles (MNPs) provides critical insights into their antimicrobial mechanisms and informs the design of safe,...

A global mitochondrial genomic atlas illuminates freshwater microeukaryote diversity

Abstract Environmental genomics has transformed our view of the microbial world, yet progress remains largely prokaryote-centric. Among microbial eukaryotes, inconsistent marker choice and limited species-level resolution blunt diversity estimates and hinder cross-study synthesis...

Quantitative Characterization of RNA-Splinted Ligation as a Multipurpose Post-Synthetic Strategy for High-Density DNA Microarrays Synthesized by Nucleic Acid Photolithography

Abstract Complex arrays of surface-immobilized DNA oligonucleotides are widely used across diverse fields of bioanalytics, particularly for their applications in massively parallel genomic assays ranging from spatial transcriptomics to protein–DNA recognition studies. DNA microar...

Brassinosteroid-regulated transcription factors confer epigenetic changes that repress plant immunity

Abstract When organisms encounter pathogens, they rapidly activate complex defense programs to ensure survival. While these immune responses are vital, they often also incur trade-offs, such as reduced growth and development and must therefore be tightly controlled 1,2 . In this...

In vitro metabolic signaling in two intestinal bacterial isolates: glutamate-driven transcriptional and functional reprogramming in Clostridium butyricum and Bacteroides thetaiotaomicron

ABSTRACT Monosodium glutamate (MSG; L-glutamate monosodium salt) is among the most widely used flavor enhancers, yet its molecular effects on gut microbial physiology remain poorly understood. Here, we examined the strain-specific transcriptomic and metabolic responses of Clostri...

Elucidating the Impact of Bacterial Composition and Diversity on Skin Homeostasis Using a Human 3D In Vitro Skin Model

The importance of the skin microbiome in human health has become increasingly evident. Despite considerable advancements, complex host–microbe interactions remain largely unexplored, primarily due to a paucity of models mimicking human skin and maintaining bacterial diversity in...