Laurentian University

High-Dose Gestational Irradiation Disrupts Fetal Mouse Brain Structure and Region-Specific Transcriptomic Profiles

Background/Objectives: Prenatal exposure to ionizing radiation can disrupt neurodevelopment, yet the region-specific structural and molecular responses of the developing brain remain incompletely understood. In particular, how gestational irradiation alters transcriptional progra...

The use of real‐world data in health services research for dementia care: A scoping review

Abstract Health services research (HSR) is critical to informing dementia care and often relies on real‐world data (RWD); however, RWD use in HSR has not been systematically mapped in the United States. Following previous researchers and Preferred Reporting Items for Systematic R...

Circulating Tumor DNA (ctDNA) for Minimal Residual Disease (MRD) Detection in Colorectal Cancer (CRC): Current Evidence, Clinical Applications, and Future Directions

Minimal residual disease (MRD) is a major contributor to colorectal cancer (CRC) recurrence following curative-intent treatment, yet conventional surveillance methods may fail to detect residual disease at its earliest stages. Circulating tumor DNA (ctDNA) has emerged as a minima...

Exploring the Mechanisms of in-Hospital Emergency Department Diversion: A Qualitative Single-Case Study

Healthcare workers (HCWs) are at risk of substance use disorders (SUD) due to factors such as burnout, stress, and occupational trauma, which may contribute to drug diversion (theft or unauthorized redirection of controlled substances), placing HCWs at risk of overdose, death, pr...

Rewriting the history of the invasive spiny water flea in North America

Introduced species cause significant environmental impacts, making timely detection key for mitigation. The spiny water flea, Bythotrephes longimanus , is considered one of the most ecologically and economically destructive species in North American freshwaters. For decades, mana...

Personal health impacts of adventurous outdoor learning

Abstract This article examines the burgeoning field of study exploring links between health, wellbeing, and adventurous outdoor learning. Key terms (outdoor learning, adventure, nature, health, wellbeing, and wellness) are defined before delving into dimensions of wellbeing that...

A strengths-based approach to understand behaviors in group work

I currently have a psychiatry resident training with me. One of the reasons that I was happy to take this training on, was to hopefully influence someone trained in a medical model in a more streng...

Maximal O2 Uptake Is Higher During Whole-Body Compared to Lower-Body Exercise due to Higher Convective, but not Diffusive, O2 Transport

PURPOSE: Maximal O2 uptake (V̇O2max) is higher during whole-body compared to lower-body large muscle mass exercise. However, whether this is explained by differences in convective or diffusive O2 transport is unclear. We examined differences in components of the O2 pathway and mu...

Crayfish populations as an indicator of littoral zone recovery in historically acidified lakes with and without predatory fish in the Killarney Region, Ontario

Killarney Provincial Park, Ontario suffered extensive aquatic biodiversity loss in the early 1960s from acidification, particularly in the highly sensitive ridgetop lakes. In recent decades, effective North American legislation and emission reductions have resulted in substantial...

Perceived Environmental Benefits and Electric Vehicle Intentions in Canada: Separate Analyses of Car Owners’ Purchase Likelihood and Non-Car Owners’ Stated Preference

Believing that electric vehicles (EVs) benefit the environment may be associated with EV intentions, but current car owners and non-car owners answer different practical questions. This cross-sectional online survey of 328 adults residing in Canada therefore analyzes the groups s...

Terminology for describing the 24-h cycle of physical activity, sedentary behaviour, and sleep: a scoping review

Abstract Background Physical activity, sedentary behaviour, and sleep are three behaviours which occupy the 24-h cycle and interact to influence a multitude of health outcomes. Different terms are currently used to describe these behaviours collectively (e.g., movement behaviours...

Throw, sweep, thrive and belong: A small story narrative analysis of sense of community meanings for elite curler mothers on Instagram

To advance understanding of socially constructed motherhood and sport, researchers are exploring elite athlete mothers’ sporting comebacks on social media (e.g. Instagram). The role of community aspects (e.g. belongingness, trust) linked to athlete mothers’ sporting career negoti...