Laiko General Hospital of Athens

Optimizing management strategies for T4b esophageal cancer: the role of TEVAR in multimodal treatment approaches

BACKGROUND: T4b esophageal cancer with aortic invasion remains a major therapeutic challenge because treatment-related tumor regression may precipitate aortoesophageal fistula formation and catastrophic hemorrhage. While chemoradiotherapy is the backbone of disease control, the r...

Treatment of male osteoporosis: a narrative review and position statement by the ECTS Clinical Action Group.

Osteoporosis in men is under-recognized and under-treated despite a substantial disease burden and poorer fracture-related outcomes than in women. Secondary osteoporosis is highly prevalent in men, making the identification and management of underlying causes essential. Bone mine...

Cause of death in a contemporary cohort of patients with pulmonary arterial hypertension

Abstract Background In pulmonary arterial hypertension (PAH), contemporary risk tools primarily estimate all-cause mortality, offering limited insight into what patients die from. Aims We aimed to characterize causes of death across baseline risk strata and to examine baseline fa...

Circulating Tumor DNA for Minimal Residual Disease Detection and Recurrence Prediction in Upper Gastrointestinal Cancers: A Scoping Review

Circulating tumor DNA (ctDNA) is a promising non-invasive biomarker for detecting minimal residual disease (MRD) and predicting recurrence after curative treatment, yet evidence in esophageal squamous cell carcinoma (ESCC), esophageal adenocarcinoma (EAC), and gastric cancer has...

Green Surgery: Current Evidence, Challenges, and Future Directions

Climate change has been identified by the World Health Organization (WHO) as “the single greatest health threat to humanity”. To investigate this subject, we conducted a narrative review of the literature about sustainability in the OR, with the aim of exploring the existing know...