Laboratoire de Biométrie et Biologie Evolutive

Assessing a local vaccination initiative: Eight years of “Immuniser Lyon” in France

“Immuniser Lyon” (IL) is a French city-level initiative launched in 2015 to promote vaccination through coordinated, locally tailored actions. The objective of this study is to describe and compare temporal trends in vaccine coverage for HPV and influenza in the Rhône area versus...

Spatiotemporal variation of the chick mass-brood size trade-off in the little owl

Abstract Resources are limited and cannot be used for multiple functions simultaneously, leading to trade-offs between life-history traits. The detection of such trade-offs depends on resource acquisition (total amount of resources) and allocation (distribution of resources betwe...

Oak masting under climate change: when spatially heterogeneous shifts in flowering phenology reshape pollen limitation

Masting, the irregular, synchronised production of seeds within tree populations, drives forest regeneration and ecosystem dynamics. Its response to climate change may depend on phenological shifts in key reproductive stages, yet this link remains poorly understood. Using 30 yr o...

Vancomycin optimised dosing regimens for critically ill patients receiving renal replacement therapy

Optimal dosing of vancomycin in critically ill patients receiving renal replacement therapy (RRT) is uncertain due to high pharmacokinetic variability. We aimed to develop individualised vancomycin dosing recommendations that optimise efficacy while minimising toxicity. Prospecti...