LabCorp (United States)

Combined Associations of Glycoprotein Acetylation With Lipoprotein (a) and hs‐CRP (High‐Sensitivity C‐Reactive Protein) on Risk of Cardiovascular Disease in MESA

BACKGROUND: Higher plasma glycoprotein acetylation (GlycA) concentrations are associated with an increased risk for incident cardiovascular disease (CVD). We investigated the combined associations of GlycA with lipoprotein (a) (Lp[a]) and hs-CRP (high-sensitivity C-reactive prote...

Toward clinically actionable lupus biomarkers: a roadmap for research, validation, and translation

Abstract Despite advances in lupus biomarker research, clinical translation has remained limited, leading to delayed diagnosis, imprecise disease monitoring, and trial-and-error treatment approaches. This roadmap, developed by the Lupus Research Alliance’s Biomarker Roadmap Commi...

Scientific perspectives on in vivo developmental neurotoxicity testing: study design, regulatory context, and future directions

Developmental neurotoxicity (DNT) potential of (agro)chemicals is assessed in rodents according to OECD Test Guidelines (TG) 426 (DNT) or 443 (Extended One-Generation Reproductive Toxicity; EOGRTS) incorporating a DNT cohort. While the EOGRTS evaluates reproductive and neurotoxic...

Gyroporus binkatensis and Cyanoboletus sulcatipes , Two New Boletes From District Swat, Pakistan, Based on Morphological and Molecular Phylogenetic Analysis

Two novel boletes, Gyroporus binkatensis and Cyanoboletus sulcatipes , are described from District Swat, Pakistan, based on detailed macro‐ and micromorphological observations and phylogenetic analysis derived from Oxford Nanopore sequencing. G. binkatensis is characterized by an...