L V Prasad Eye Institute

Epigenetic Factor Dysregulation and Distinct Expression Signatures in Retinoblastoma: A Transcriptomic Analysis

Purpose: Transcriptional heterogeneity observed in retinoblastoma (RB) is unexplained by the limited genetic alterations identified. Epifactors, which can modulate transcriptional activity and oncogenic pathways, may contribute to this heterogeneity. However, knowledge regarding...

Inherited Retinal Dystrophy in an 11-month-old Infant with Yunis-Varon Syndrome and Homozygous FIG4 Mutation

Purpose: Inherited retinal dystrophies (IRDs) may present as isolated entities or as multisystem syndromes. Yunis-Varon syndrome (YVS), seen with homozygous FIG4 mutations, is a rare autosomal recessive disorder. Herein, we report a case of YVS associated with early-onset rod-con...

Effects of Morning and Evening Narrowband Blue Light and Myopic Defocus on Axial Length in Humans

Purpose To investigate the effects of morning and evening narrowband blue light exposure on axial length, and to examine the short-term effect of morning blue light combined with myopic defocus on axial length.Methods For objective 1, 18 individuals underwent 60 minutes of narrow...