Kyushu Kyoritsu University

osa-miR166g-3p Mimic Reduces Hepatic Triglyceride Accumulation in Mice

Abstract Hepatic triglyceride accumulation reflects an imbalance in hepatic lipid metabolism, and pharmacological approaches that enhance fatty acid utilization may provide a strategy for reducing excessive lipid accumulation in the liver. Here, we evaluated the effects of a synt...

Denitrative Cyanation of Nitroalkanes by Nucleophilic Substitution through Anion–Radical Coupling

Abstract We report a photocatalytic denitrative cyanation to directly convert nitroalkanes into nitriles under mild conditions. The reaction proceeds rapidly under blue LED irradiation and exhibits broad functional-group tolerance. Mechanistic investigations support an anion–radi...