Kyorin University

Real-World Versus Centers for Medicare and Medicaid Services Estimates of Pediatric Retinal Detachment Repair Times

Purpose: To compare real-world pediatric retinal detachment (RD) repair times with the Centers for Medicare and Medicaid Services (CMS) estimates for complex RD surgeries. Methods: A cross-sectional survey was performed of complex pediatric RD perioperative times from pediatric r...

Factors predicting consultation for obstructive sleep apnea among Japanese male workers in the construction and civil engineering sector: a longitudinal study using annual medical check-up data

Abstract Objectives Research on predictors for consultations regarding obstructive sleep apnea (OSA) is limited, with few longitudinal studies examining how changes in disease status and work conditions influence these behaviors. This study tracked Japanese male workers in the co...

Inverted urothelial papilloma: Diagnostic challenges, molecular insights, and clinical implications.

mutations, challenging the long-held assumption that these cells are morphologically and genetically normal. Future studies should investigate whether similar genetic alterations in morphologically normal urothelium occur in other urothelial tumors. This could refine understandin...

Working conditions, career barriers and perceived equity among neuro-oncology professionals: insights from the Japan society for neuro-oncology (JSNO) gender equality and diversity committee survey

<title>Abstract</title> Background Gender equity, work–life balance, and career development have become important concerns in the medical profession. However, empirical evidence on how neuro-oncology professionals experience working conditions, career barriers, and perceived ineq...

Serum periostin levels in myocardial infarction: Findings from forensic autopsy cases

Acute myocardial infarction (AMI) remains one of the leading causes of sudden death with significant implications in both clinical and forensic practice. In forensic settings, AMI diagnosis traditionally relies on gross and histopathological findings. However, when ischemic chang...

Risk and Impact of Cytomegalovirus Infection in Bullous Pemphigoid Patients Treated With Immunosuppressive Agents

ABSTRACT Severe infection is associated with increased mortality in patients receiving systemic corticosteroid therapy, including those with bullous pemphigoid (BP). Cytomegalovirus (CMV) reactivation represents a highly probable and underrecognized cause of death in immunosuppre...

Icotrokinra (ICO), a Novel Targeted Oral Peptide, in Patients (Pts) with Psoriatic Disease: Exploratory Assessments from a Phase 2 Psoriasis (PsO) Study Informing a Phase 3 Clinical Program in Psoriatic Arthritis (PsA)

Objectives PsA affects ~20-30% of patients with PsO, causing articular inflammation and impaired quality of life. ICO, a novel targeted oral peptide that binds IL-23 receptor, showed greater clinical response rates vs placebo and a favorable safety profile in moderate-to-severe p...