Kurashiki Central Hospital

Coronal Alignment and Ulnar Deviation After Radial-Sided Lateral-Approach Silicone Arthroplasty of the Proximal and Distal Interphalangeal Joints: A Prospective Case Series

Background: Following radial-sided lateral exposure for interphalangeal silicone arthroplasty, the repaired radial collateral ligament must maintain coronal stability against postoperative ulnar drift. Prospective direction-specific alignment data are limited. Methods: Consecutiv...

2026 revised CVIT clinical expert consensus on drug coated balloons for coronary artery disease

Abstract Drug-coated balloons (DCBs) are attracting attention as a therapeutic alternative to drug-eluting stents (DES) in percutaneous coronary interventions. DCB technology allows direct delivery of antiproliferative drugs to the vessel wall without implantation of a permanent...

Arterial wall fragment embolism following balloon-assisted coiling: A case report

Arterial wall fragment embolism is a rare complication of balloon-assisted coiling, and its underlying mechanism remains poorly understood. We report a histopathologically confirmed case of arterial wall fragment embolism during balloon-assisted coiling for a ruptured aneurysm. A...

A multicenter multistate modeling on the natural history of liver decompensation: Longitudinal analysis of 1777 patients.

BACKGROUND: Cirrhosis often remains silent until decompensation, after which survival deteriorates sharply. Contemporary, transition-aware estimates are limited, especially in Asian-predominant cohorts. We analyzed trajectories from compensated advanced chronic liver disease (cAC...

Renal function–adjusted initial JAK inhibitor dosing and outcomes in rheumatoid arthritis: from the ANSWER cohort study

INTRODUCTION/OBJECTIVES: To evaluate clinical effectiveness and treatment persistence after renal function-guided reduced-dose initiation of Janus kinase inhibitors (JAKis) in rheumatoid arthritis (RA). METHOD: We analysed 368 adults initiating a JAKi in the ANSWER registry (2013...

Transplant outcomes after intensive chemotherapy or venetoclax plus azacitidine in acute myeloid leukemia: a multicenter retrospective study in Japan

The present retrospective multicenter study in Japan evaluated the role of venetoclax plus azacitidine (V/A) before first allogeneic hematopoietic stem cell transplantation (SCT) in 144 transplant-eligible acute myeloid leukemia (AML). Thirty-seven patients received V/A prior to...

Serum C4/C3 ratio at disease onset predicts end-stage renal disease in microscopic polyangiitis: the multicentre REVEAL cohort

We investigated whether serum complement C3 and C4 levels and the C4/C3 ratio at disease onset were associated with clinical features, renal involvement, and prognosis in microscopic polyangiitis (MPA). Patients were stratified into tertiles according to baseline C3 and C4 levels...

Nivolumab plus ipilimumab-based treatment in Japanese patients with metastatic non-small cell lung cancer and tumor PD-L1 < 1%: a pooled analysis

BACKGROUND: Nivolumab plus ipilimumab-based therapies have shown long-term, durable clinical benefit in patients with metastatic non-small cell lung cancer (NSCLC), including those with tumor programmed death-ligand 1 (PD-L1) expression < 1%, a population with high unmet need. He...