KPC Medical College and Hospital

Lymphocytic choriomeningitis virus: an under-recognized arenaviral threat with important maternal–fetal implications

Lymphocytic choriomeningitis virus (LCMV), a rodent-borne arenavirus first identified in 1933, remains a neglected zoonotic pathogen of growing recognition in urban, non-endemic regions. Although typically associated with rural rodent exposure, recent epidemiological data indicat...

Agreement Between Venous and Capillary Haemoglobin Concentrations in a High-Burden Urban Indian Setting: A Cross-Sectional Analysis

Background: Anaemia is a major public health issue in India, where point-of-care testing is central to national control strategies. This study evaluated the diagnostic accuracy of the HemoCue® Hb 201+ for haemoglobin (Hb) estimation from capillary blood compared to the gold-stand...

Ethics of artificial intelligence use in dermatology research and healthcare

Artificial intelligence (AI) is transforming dermatology at a rapid pace unlike any other clinical specialty, largely because skin disease is diagnosed visually and, therefore, lends itself naturally to image-based machine learning. Convolutional neural networks now correspond wi...

Immune checkpoint inhibitors for African people living with HIV: T-cell exhaustion, endemic co-infections, and the oncology trial gap

Immune checkpoint inhibitors (ICIs) have fundamentally transformed modern oncology by unleashing the body’s anti-tumor immunity, yet people living with HIV (PLWH) were systematically excluded from the pivotal registration trials. This evidence gap is especially consequential in s...

Hybrid endoscopic submucosal dissection enhances efficiency with comparable curative outcomes: a Bayesian meta-analysis, systematic review, and Monte Carlo simulation of randomized controlled trials

Background/Aims: Gastrointestinal (GI) cancers accounted for 3.24 million deaths worldwide in 2022. Endoscopic submucosal dissection (ESD) enables en bloc resection of early neoplasms but is time-intensive and technically challenging. Hybrid ESD (H-ESD), which combines dissection...

Effectiveness of two different innovative teaching learning methods: a comparative analysis among phase 1 MBBS students

Abstract Background Active learning strategies are increasingly incorporated into competency-based medical education to promote student engagement, collaborative learning, and higher-order cognitive skills. Although both cooperative learning methods have demonstrated educational...

A prospective comparative study of different nephrolithometric scoring system for nephrolithiasis to predict stone free status and complications in supine PCNL

The significant rise in stone disease has led to an increased popularity of percutaneous nephrolithotomy for the management of substantial stone burdens. Despite ongoing advancements in technology and surgical methods, overall complication rates of PCNL have gone up. For the best...