Korean Association Of Science and Technology Studies

Explainable Deep Learning Reveals Future Changes in East Asian Extreme Winter Predictability

Deep learning-based approaches have emerged as powerful tools for seasonal prediction, yet their skill remains limited for extreme anomalies, and warming climates may alter predictability sources. Here we present a convolutional neural network (CNN)-based framework to assess how...

Mosapride promotes internalization of a TREK1–HTR4 complex and exerts rapid antidepressant-like effects

Major depressive disorder (MDD) remains a critical global health burden, and a substantial proportion of patients exhibit insufficient responses to conventional monoaminergic antidepressants. Selective inhibition of the two-pore domain potassium channel TREK1 has emerged as a pro...