Korea University Anam Hospital

In situ antibacterial thermosensitive hydrogel as a versatile platform for diabetic wound therapy and molecular monitoring

Chronic diabetic wounds are difficult to manage because of persistent inflammation, impaired tissue regeneration, and high infection risk under hyperglycemic conditions. Microbial colonization further aggravates inflammatory responses and disrupts the normal progression of wound...

Incidence, risk factors, and mortality of acute kidney injury in patients receiving immune checkpoint inhibitors: analysis by acute kidney injury subtype

Background: Acute kidney injury (AKI) is a common complication in patients receiving immune checkpoint inhibitor (ICI) therapy. It can result from conventional causes or immune-mediated mechanisms. This study aimed to determine the incidence, risk factors, and clinical outcomes o...

Circadian misalignment and low-grade inflammation: Failure of temporal gating by the molecular clock

Circadian misalignment, from shift work, recurrent sleep-wake disruption, or mistimed behavioral rhythms, tracks with cardiometabolic disease and low-grade systemic inflammation, yet no single account ties the molecular, animal, and human evidence together. This narrative review...

Association of Estimated Arterial Stiffness with Collateral Status and Functional Outcome after Endovascular Thrombectomy: A Secondary Analysis of the OPTIMAL-BP Trial

PURPOSE: Estimated pulse wave velocity (ePWV) is a surrogate of arterial stiffness that may influence stroke outcomes and potentially affect collateral circulation. We examined the association of ePWV with collateral status and 3-month functional outcome after successful endovasc...

Radiologic capsular abnormalities on shoulder MRI: associations with rotator cuff and biceps tendon tears and implications for the diagnosis of adhesive capsulitis

Capsular abnormality on shoulder MRI may suggest adhesive capsulitis, but similar findings can occur in patients with other shoulder pathologies such as rotator cuff tears. This study investigated the clinical and imaging factors associated with radiologic capsular abnormality (R...

Comparative study on the clinical effectiveness of low-concentration cyclosporine eye drops in patients with dry eye disease

Purpose This study aimed to evaluate the efficacy and safety of low-concentration, nanoparticle-based cyclosporine eye drops (SCAI-001 0.01% and SCAI-001 0.02%) compared to those of the conventional Restasis ® (cyclosporine 0.05%) emulsion for dry eye disease (DED). Methods In th...

Comparison of Uncovered and Covered Biliary SEMS for the Salvage of Obstructed SEMS: A Multicenter Retrospective Propensity Score–Weighted Study

BACKGROUND AND AIMS: Recurrent biliary obstruction (RBO) is common after uncovered self-expandable metal stent (UCSEMS) placement in unresectable distal malignant biliary obstruction. We compared stent patency, clinical outcomes, and RBO patterns between fully covered (FCSEMSs) a...